“…21 The next paper in the present issue by Lundbech et al aims to get behind the potential increased VTE risk in HIPEC and reviews the effect of HIPEC on hemostatic activation. 22 The authors conclude that possible mechanisms behind increased VTE risk are an increased acute response, indicated by increased factor VIII and fibrinogen, and possibly impaired fibrinolysis. HIPEC did not greatly influence standard coagulation markers or platelet count, while dynamic assays of platelet activation, thrombin generation, or fibrin formation have only been sparsely researched.…”