Changes in clinicopathological features and survival after gastrectomy for gastric cancer over a 20-year period

Ahn, Hye Young; Lee, H.-J.; Yoo, Myoung-Woo; Jeong, Sook‐Hyang; Park, D.-J.; Kim, H.-H.; Kim, W. H.; Lee, K. U.; Yang, Han Kwang

doi:10.1002/bjs.7310

Cited by 172 publications

(116 citation statements)

References 32 publications

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“…The age and gender proportions of the subjects were similar to those in our previous studies [1,15]. Local and systemic complications until POD30 are summarized in Table 2.…”

Section: Resultssupporting

confidence: 70%

“…Direct transfusion-related complications include pulmonary complications, compromised immune status, and the transmission of infectious diseases. However, some studies have reported several other transfusion-related complications [15,16]. In our study, we only analyzed complications that developed up to postoperative day 30; thus excluding those that could likely not be attributable to the acute effects of transfusion.…”

Section: Discussionmentioning

confidence: 99%

“…A simple hospital course deviation (grade 1) was not regarded as an event, whereas those requiring medical or surgical interventions (grade 2 or higher) were regarded as events. Morbidity was classified as follows: (1) local complications including wound infection, fluid collection/abscess, anastomosis leakage, stenosis, intestinal obstruction, ileus, intraluminal bleeding, intraabdominal bleeding, and pancreatitis; and (2) systemic complications including pulmonary, renal, urinary, cardiac, and neurologic problems, as defined in our previous study [14][15][16].…”

Section: Patients Materials and Methodsmentioning

confidence: 99%

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Impact of perioperative hemoglobin levels on postoperative outcomes in gastric cancer surgery

et al. 2012

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Background The aim of this study was to evaluate the association of postoperative blood transfusion and anemia with postoperative outcomes in gastric cancer surgery. Methods We enrolled 588 patients who had undergone curative resection for gastric cancer. Input variables for risk assessment consisted of 3 categories: patient demographics, surgical and pathological factors, and anemia-related factors. Postoperative outcomes included 30-day morbidity and mortality. Univariate and multivariate analyses were performed to identify risk factors influencing postoperative complications. Results The rate of total complications was 19.0 %. Comorbidity, lowest hemoglobin (Hb) level from the operative day up to postoperative day 7 (LOW-Hb), the percentage of drop in Hb level on postoperative day 2 (POD2-Hb change), and postoperative transfusion were independent risk factors in the multivariate analysis, with LOW-Hb and postoperative transfusion found to be the most significant factors. When LOW-Hb was C9.0 g/dL, postoperative complications were higher in the transfused group than in the non-transfused group (60.0 vs. 14.2 %, respectively, p = 0.024), but when LOW-Hb was\9.0 g/dL, postoperative complications were not different between the 2 groups (44.6 vs. 37.5 %, p = 0.525). ConclusionThe lowest postoperative Hb level and postoperative transfusion were the most significant risk factors for postoperative complications in gastric cancer surgery.

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“…The age and gender proportions of the subjects were similar to those in our previous studies [1,15]. Local and systemic complications until POD30 are summarized in Table 2.…”

Section: Resultssupporting

confidence: 70%

Section: Discussionmentioning

confidence: 99%

Section: Patients Materials and Methodsmentioning

confidence: 99%

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Impact of perioperative hemoglobin levels on postoperative outcomes in gastric cancer surgery

et al. 2012

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“…As the incidence of proximal gastric cancer has recently increased, proximal gastrectomy (PG) is widely accepted as a function-preserving surgery for proximal EGC [57][58][59] . In spite of functional benefits such as improved postoperative nutrition, preventing anemia, and release of gut hormones, PG has not gained in popularity, mainly due to postoperative complications such as esophageal reflux and anastomotic stricture [60][61][62][63][64] .…”

Section: Gastrectomymentioning

confidence: 99%

“…The 3-year recurrence-free survival was similar between LADG and LAPPG (98.8% vs 98.2%, P = 0.702), but decrease in serum protein and albumin levels at 1 to 6 mo postoperation and abdominal fat volumes at 1 year postoperation were significantly greater in LADG than in LAPPG. They concluded that for middle-third EGC, LAPPG can be considered a superior treatment option over LADG in terms of nutritional advantage and a lower incidence of gallstone.As the incidence of proximal gastric cancer has recently increased, proximal gastrectomy (PG) is widely accepted as a function-preserving surgery for proximal EGC [57][58][59] . In spite of functional benefits such as improved postoperative nutrition, preventing anemia, and release of gut hormones, PG has not gained in popularity, mainly due to postoperative complications such as esophageal reflux and anastomotic stricture [60][61][62][63][64] .…”

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confidence: 99%

Minimally Invasive Surgery of Gastric Cancer

Güner

Hyung

2017

Minimally Invasive Surgery for Upper Abdominal Cancer

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Minimally invasive surgery for gastric cancer has rapidly gained popularity due to the early detection of early gastric cancer. As advances in instruments and the accumulation of laparoscopic experience increase, laparoscopic techniques are being used for less invasive but highly technical procedures. Recent evidence suggests that the short-and long-term outcomes of minimally invasive surgery for early gastric cancer and advanced gastric cancer are comparable to those of conventional open surgery. However, these results should be confirmed by large-scale multicenter prospective randomized controlled clinical trials.© 2014 Baishideng Publishing Group Inc. All rights reserved. Key words: Gastric cancer; Minimally invasive surgery; Laparoscopic gastrectomyCore tip: Minimally invasive surgery has become an alternative modality for the treatment of gastric cancer.Son SY, Kim HH. Minimally invasive surgery in gastric cancer. World J Gastroenterol 2014; 20(39): 14132-14141 Available from: URL: http://www.wjgnet.com/1007-9327/full/ v20/i39/14132.htm DOI: http://dx.doi.org/10.3748/wjg.v20. tano et al [9] and Nagai et al [10] reported the success of laparoscopy-assisted distal gastrectomy (LADG) for EGC in 1994 and 1995. In the early 2000s, robot-assisted surgery emerged as one of the treatment modalities for EGC, and the first robot-assisted gastrectomy (RAG) for EGC was reported by Hashizume et al [11] in 2003. In 2011, singleincision laparoscopic surgery was described for EGC [12] . MIS has revolutionized the surgical approach to gastric cancer for the past two decades, leading to improvements in patients' quality of life by producing less pain, less blood loss, earlier postoperative recovery, and a shorter hospital stay [13][14][15][16][17][18][19] .Currently, MIS is evolving in two major directions [20] . First, MIS techniques are being used in more radical but less invasive procedures, such as totally laparoscopic distal gastrectomy or laparoscopic total gastrectomy with D1+ or D2 lymphadenectomy. These procedures are comparable to conventional open surgery and can be performed even in patients with advanced gastric cancer (AGC) [21][22][23] . Second, MIS is being employed for function-preserving surgery, including pylorus-preserving gastrectomy (PPG), proximal gastrectomy, and limited gastrectomy with sentinel node navigation surgery. These procedures can assist in improving patients' late postoperative function and quality of life [20,[24][25][26] . RECENT ADVANCES IN LAPAROSCOPIC GASTRECTOMYAs advances in instruments and the accumulation of laparoscopic experience increase, laparoscopic techniques are being used for less invasive but highly technical procedures. Totally laparoscopic gastrectomy (TLG) is one example. TLG has gained popularity since Kanaya et al [27] reported the first delta-shaped anastomosis. A recent meta-analysis (five studies, 652 patients) showed that totally laparoscopic distal gastrectomy has less bleeding, shorter time to first flatus, and lower rates of postoperative complicat...

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Current status of proximal gastrectomy for gastric and esophagogastric junctional cancer: A review

Nunobe

Ida

2020

Annals of Gastroent Surgery

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Changes in clinicopathological features and survival after gastrectomy for gastric cancer over a 20-year period

Abstract: The mean age of patients with gastric cancer has increased during the past 20 years. The proportion of early gastric cancer and overall survival have gradually increased, especially in patients aged over 40 years.

Cited by 172 publications

References 32 publications

Impact of perioperative hemoglobin levels on postoperative outcomes in gastric cancer surgery

Impact of perioperative hemoglobin levels on postoperative outcomes in gastric cancer surgery

Minimally Invasive Surgery of Gastric Cancer

Current status of proximal gastrectomy for gastric and esophagogastric junctional cancer: A review

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