Changes in Choroidal Thickness after Cataract Surgery

Ibrahim, Asmaa M; Elgouhary, Sameh Mohamed; Nassar, Moustafa Kamal; Batanony, Ahmed Helmy El

doi:10.1080/08820538.2017.1416410

Cited by 22 publications

(18 citation statements)

References 23 publications

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“…Further, significant decrease of TNEP and ML in CC (Additional file 1: Table S5) could result from increased demand in heat dissipation through opening of anastomoses corroborating with published studies [2,16,26]. Some authors hypothesized increase in subfoveal thickness to be a consequence of local choroidal inflammatory response but found no reasoning for these changes, while correlation to CDE was not reported [18,25,27].…”

Section: Choroidsupporting

confidence: 76%

“…However, none of these studies actually measured the local release of inflammatory metabolites. On the contrary, the prevailing view modelled from our study results' was that increase in macular hemodynamics could not be the result of postoperative inflammation as the changes persisted three months after the surgery, when inflammatory response should have been over [2,15,[17][18][19], nor decrease in IOP due to OPP consistency (Additional file 1: Table S2) [3]. Moreover, all patients underwent uncomplicated phacoemulsification with favorable, low PHACO time and CDE (Additional file 1: Table S1), while factors contributing to neural damage and blood-brain barrier breakdown were excluded prior to enrolment.…”

Section: Functional Hyperaemiacontrasting

confidence: 59%

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Macular perfusion analysed by optical coherence tomography angiography after uncomplicated phacoemulsification: benefits beyond restoring vision

et al. 2021

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Background The purpose of the study is to investigate the changes of macular perfusion by OCT-angiography (OCT-A) after uncomplicated phacoemulsification. Methods OCT-A was performed before cataract surgery, 1 week, 1 month, and 3 months after surgery recording superficial vascular complex (SVC), nerve fiber layer vascular plexus (NFLVP), superficial vascular plexus (SVP), deep vascular complex (DVC), intermediate capillary plexus (ICP) and deep capillary plexus (DCP), as well as large choroidal blood vessels and choriocapillaris (CC). Explant area (EA), vessels area (VA), vessels percentage area (VPA), total number of junctions (TNJ), junctions density (JD), total vessels length (TVL), average vessels length (AVL), total number of end points (TNEP), and mean lacunarity (ML) throughout all layers were analysed. Results Significant changes of vascular parameters in 55 eyes of 55 patients mostly reached plateau one week after surgery and remained stable up to 3 m after surgery, occurring in all retinal layers but not in choroid and CC. The greatest increase in VPA (22.79%), TVL (16.71%), AVL (166.71%) and JD (29.49%) was in SVC. On the contrary, the greatest change of ML (− 53.41%) appeared in DVC. Conclusions This is the first OCT-A study demonstrating perfusion alterations in macula after phacoemulsification due to functional hyperaemia. We presume the effect is evoked by increased light intensity stimulation of retina after cataract removal. Accordingly, phacoemulsification in elderly population could have advantageous feature in addition to restoring visual acuity.

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Section: Choroidsupporting

confidence: 76%

Section: Functional Hyperaemiacontrasting

confidence: 59%

Macular perfusion analysed by optical coherence tomography angiography after uncomplicated phacoemulsification: benefits beyond restoring vision

et al. 2021

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“…Other authors have analyzed postoperative CT changes in eyes without retinal pathology and found a significant increase in CT. Some authors have declared a prolonged significant increase in subfoveal CT (SFCT) after phacoemulsification [20,29,30]. Similar to our results, Abdellatif and coworkers have published that SFCT increased statistically significantly after 1 month (p = 0.014) with no significant change 3 months after the surgery (p = 0.073) [21].…”

Section: Discussionsupporting

confidence: 89%

Phacoemulsification Induced Changes of Choroidal Thickness in Eyes with Age-Related Macular Degeneration

et al. 2020

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Background and Objectives: Patients with cataract and age-related macular degeneration (AMD) may safely undergo cataract phacoemulsification to enhance visual acuity. Although it has not been proven that cataract surgery can cause AMD progression, different phacoemulsification effects are observed not only on retinal but also on choroidal tissues. The purpose of this study was to evaluate the effect of phacoemulsification on the choroidal thickness (CT) in eyes with and without AMD. Materials and Methods: In 32 eyes of 32 patients with senile cataract (No-AMD group) and in 32 eyes of 32 patients with cataract and dry AMD (AMD group), who had phacoemulsification without intraoperative complications and intraocular lens implantation, foveal retinal thickness (FRT) and CT were evaluated three times: at 1–2 post meridiem preoperatively, then 1 month and 3 months postoperatively, using 1050 nm swept source-optical coherence tomography (Topcon, Tokyo, Japan). Results: In both groups, a significant increase in FRT was observed after one month and a decrease after three months without reaching the baseline. One month after surgery, a sectorial CT increase was apparent in all sectors in both groups. A negative association between CT and age was disclosed in the No-AMD group almost for all regions at all time points. Furthermore, CT was significantly negatively associated with axial length (AL) in all sectors at all time points in the AMD group. Conclusion: Uneventful phacoemulsification may induce changes in the posterior eye segment. An increase in CT and FRT was observed in both groups one month after the surgery. However, three months after surgery, CT changes were different in both groups, while FRT decreased in both groups. CT changes negatively associated with age in the No-AMD group and with AL in the AMD eyes. These postoperative changes in the choroid and retina may not only lead to the late-onset pseudophakic cystoid macular edema but also to progression of AMD.

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“…Further, signi cant decrease of TNEP and ML in CC (Additional le 1: Table S5) could result from increased demand in heat dissipation through opening of anastomoses corroborating with published studies [2,16,26]. Some authors hypothesized increase in subfoveal thickness to be a consequence of local choroidal in ammatory response but found no reasoning for these changes, while correlation to CDE was not reported [18,25,27].…”

Section: Choroidsupporting

confidence: 77%

“…However, none of these studies actually measured the local release of in ammatory metabolites. On the contrary, the prevailing view modelled from our study results' was that increase in macular hemodynamics could not be the result of postoperative in ammation as the changes persisted three months after the surgery, when in ammatory response should have been over [2,15,[17][18][19], nor decrease in IOP due to OPP consistency (Additional le 1: Table S2) [3]. Moreover, all patients underwent uncomplicated phacoemulsi cation with favorable, low PHACO time and CDE (Additional le 1: Table S1), while factors contributing to neural damage and blood-brain barrier breakdown were excluded prior to enrolment.…”

Section: Discussioncontrasting

confidence: 63%

Macular Perfusion Analysed by Optical Coherence Tomography Angiography after Uncomplicated Phacoemulsification: Benefits beyond Restoring Vision

Križanović

Bjeloš

Bušić

et al. 2020

Preprint

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Background: The purpose of the study is to investigate the changes of macular perfusion by OCT-angiography (OCT-A) after uncomplicated phacoemulsification.Methods: OCT-A was performed before cataract surgery, 1 week, 1 month, and 3 months after surgery recording superficial vascular complex (SVC), nerve fiber layer vascular plexus (NFLVP) superior vascular plexus (SVP), deep vascular complex (DVC), intermediate capillary plexus (ICP) and deep capillary plexus (DCP), as well as large choroidal blood vessels and choriocapillaris (CC) were recorded. Explant area (EA), vessels area (VA), vessels percentage area (VPA), total number of junctions (TNJ), junctions density (JD), total vessels length (TVL), average vessels length (AVL), total number of end points (TNEP), mean E lacunarity (MEL), and foveal avascular zone (FAZ) area throughout all layers were analysed.Results: Significant changes of vascular parameters in 55 eyes of 55 patients mostly reached plateau one week after surgery and remained stable up to three months after surgery, occurring in all retinal layers but not in choroid and choriocapillaris. Changes of FAZ area ensued across all retinal layers within one month after surgery. The greatest increase in VPA (22.79%), TVL (16.71%), AVL (166.71%) and JD (29.49%) was in SVC causing the largest FAZ surface decrease (-25.54%) in SVC likewise. On the contrary, the greatest change of MEL (-53.41%) appeared in DVC.Conclusions: This is the first OCT-A study demonstrating that perfusion alterations observed in macula after phacoemulsification are response to functional hyperaemia prompted by augmented visual stimulation. Phacoemulsification in elderly population proved as advantageous feature in addition to restoring visual acuity.

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Changes in Choroidal Thickness after Cataract Surgery

Abstract: Mean SFCT increased after cataract surgery. The changes in SFCT return to near the baseline after 3 months.

Cited by 22 publications

References 23 publications

Macular perfusion analysed by optical coherence tomography angiography after uncomplicated phacoemulsification: benefits beyond restoring vision

Macular perfusion analysed by optical coherence tomography angiography after uncomplicated phacoemulsification: benefits beyond restoring vision

Phacoemulsification Induced Changes of Choroidal Thickness in Eyes with Age-Related Macular Degeneration

Macular Perfusion Analysed by Optical Coherence Tomography Angiography after Uncomplicated Phacoemulsification: Benefits beyond Restoring Vision

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