Changes in cerebellar purkinje cells during postresuscitation period: Morphometric and ultrastructural analysis

Abstract

Morphometric and electron microscopic analysis of rat cerebellar Purkinje cells was carried out after external neurological recovery following 10-min systemic circulation arrest caused by clamping cardiac vascular bundle, in order to elucidate the mechanisms of delayed encephalopathies. The composition of Purkinje cell population notably changed during the postresuscitation period. Ultrastructural disorders in these neurons, persisted for 1 month after resuscitation.