Changes in cardiac troponin I (cTnI), T (cTnT), and some biochemical parameters in Arabian racehorses after training

Abstract

The aim of this study was to compare the changes in the content of cTnI, cTnT and some biochemical parameters (CK–MB, LDH, AST, ALT) in Arabian racehorses before and after training. Diagnosis of myocardial disease in horses is very difficult due to the lack of specific cardiac signs. Cardiac diseases are seen as a cause of sudden death or decreased performance in horses. It has also been reported that excessive exercise may cause transient myocardial damage. In our study, 20 healthy stallion Arabian racehorses aged 4–10 y (6.00 ± 0.52 y) were used. Five millilitres of blood was collected from the V. jugularis of clinically healthy horses into serum tubes before and after training. Training time was determined as 30 min for each horse. Pre-training cTnI, cTnT, CK–MB, LDH, AST, and ALT contents were determined to be 0.130 ± 0.01 ng/mL, 0.007 ± 0.00 ng/mL, 231.15 ± 8.96 U/L, 692.45 ± 34.12 U/L, 309.92 ± 18.48 U/L, and 11.83 ± 0.92 U/L, respectively. After training, cTnI, cTnT, CK–MB, LDH, AST, and ALT contents were determined to be 0.169 ± 0.01 ng/mL, 0.008 ± 0.00 ng/mL, 289.80 ± 10.96 U/L, 704.25 ± 22.03 U/L, 328.47 ± 19.58 U/L, and 15.24 ± 1.03 U/L, respectively. As a result, it was determined that exercise triggered myocardial damage to some extent in Arabian horses. Exercise stimulates troponin release and the differences that may occur in troponin tests in horses after exercise should be taken into consideration.

Physiological and metabolic responses in Kök‐Börü horses: Correlations with game outcomes

“…In a study by Ayvazoğlu et al. ( 2023 ) on Arabian racehorses, biochemical data were taken before and after a 30‐min training session. They reported pre‐training levels of creatine phosphokinase (CK‐MB), lactate dehyrogenase (LDH), aspartat aminotransferase (AST) and Alanin Amimotransferase (ALT) as 231.15 ± 8.96, 692.45 ± 34.12, 309.92 ± 18.48 and 11.83 ± 0.92 U/L, respectively.…”

Blood-Based Markers for Skeletal and Cardiac Muscle Function in Eventing Horses before and after Cross-Country Rides and How They Are Influenced by Plasma Volume Shift

“…Studies on endurance horses [26][27][28] reported an increase in cTnI levels after endurance rides, while Fazio et al [29] found cTnI increases after jump training in healthy horses. Ayvazoglu et al [30] and Pourmohammad et al [31] found cTnI increases in Arabian and thoroughbred racehorses after training. In the context of racehorses, Rossi et al [32] demonstrated that increased cTnI concentrations and cardiac arrhythmias after racing indicate myocardial damage.…”