Changes in brain structure and function following exposure to oral LSD during adolescence: A multimodal MRI study
Lila Harris,
Zachary Smith,
Richard J. Ortiz
et al.
Abstract:Background: LSD is a hallucinogen with complex neurobiological and behavioral effects. Underlying these effects are changes in brain neuroplasticity. This is the first study to follow the developmental changes in brain structure and function following LSD exposure in periadolescence.
Methods: Female and male mice were given vehicle, single or multiple treatments of 3.3 µg of LSD by oral gavage starting on postnatal day 51. Between postnatal days 90-120 mice were imaged and tested for cognitive and motor behavi… Show more
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