Changes in blood coagulation and fibrinolysis during the postoperative period

Ygge, J

doi:10.1016/0002-9610(70)90041-3

Cited by 116 publications

(25 citation statements)

References 25 publications

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“…Although the PCV remained low throughout subsequent days, plasminogen levels started to rise to near normal levels by the third postoperativç day when PCV is still quite low. On the other hand, the fibrinolytic inhibitor alpha 2-antiplasmin did not show any significant fluctuations following surgery and this differs from the findings of others [2] who demonstrated a significant increase. Despite the decrease in the number of platelets in the immediate postoperative period, their adhesiveness and aggregation may be enhanced [3,8] thereby contributing further to the hypercoagulability [5] during the postoperative period.…”

Section: Discussioncontrasting

confidence: 99%

“…The increases in fibrinogen and factors VIII and V levels and the decrease in platelet count, especially during the first three postoperative days, are well documented [2,6,7,19]. In addition, our findings agree with the earlier studies in Swedish patients [2].…”

Section: Discussionsupporting

confidence: 93%

“…In this study, the postsurgical alterations in the plasmatic hemostatic variables in patients of Arab origin conform to a greater extent with earlier studies in Caucasians [1][2][3][4][5][6][7][8][9][10]. The increases in fibrinogen and factors VIII and V levels and the decrease in platelet count, especially during the first three postoperative days, are well documented [2,6,7,19].…”

Section: Discussionsupporting

confidence: 88%

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Hemostatic Changes Following Surgery

1992

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 88%

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Hemostatic Changes Following Surgery

1992

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“…This change in the coagulation status following surgery has been looked at in a few studies. 29,30 The changes in coagulability that occur following trauma, especially after surgery, need to be explored in more detail.…”

mentioning

confidence: 99%

Is pre-operative assessment of coagulation profile with Thrombelastography (TEG) useful in predicting venous thromboembolism (VTE) following orthopaedic surgery?

Parameswaran

Krishnamoorthy

Oommen

et al. 2016

Journal of Clinical Orthopaedics and Trauma

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“…A literatura nos mostra que, durante grandes cirurgias abdominais, cardíacas, ginecológicas, urológicas e de tumores cerebrais, há ativação da coagulação e consequente ativação secundária do sistema fibrinolítico [19][20][21][22][23][24] . Isto pode ser evidenciado no Caso 1, pelo encontro de moderado aumento nos produtos de degradação do fibrinogênio e fibrina (PDF).…”

Section: Discussionunclassified

Hematoma epidural espontâneo: relato de dois casos

Hamamoto

Nakano

Guerreiro

et al. 1998

Arq. Neuro-Psiquiatr.

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RESUMO -Os hematomas epidurais espontâneos são raramente descritos na literatura. Estão associados a doenças infecciosas do crânio, distúrbios da coagulação, malformações vasculares da dura-máter e metástases na calota craniana. Os autores relatam dois casos de hematomas epidurais espontâneos de diferentes etiologias e discutem aspectos relacionados à hemostasia.PALAVRAS-CHAVE: hematoma epidural, hematoma espontâneo, hemostasia. Spontaneous epidural hematoma: report of two casesABSTRACT -Spontaneous epidural hematomas are rarely described in literature. They are associated with infectious diseases of the skull, coagulation disorders, vascular malformations of the dura-mater and metastasis to the skull. The authors report two cases of spontaneous epidural hematoma of different etiologies, and study parameters of hemostasis.KEY WORDS: epidural hematoma, spontaneous hematoma, hemostasis.Os hematomas epidurais (HED) são considerados lesões secundárias a traumatismo craniencefálico e sua incidência varia de 0,2 a 30% de acordo com a literatura 1-3 . Cerca de 83 a 95% dos casos estão associados a fraturas de crânio 2-5 ; porém, quando não há história ou sinais de traumatismo e na ausência de fraturas de crânio, pode-se dizer que o HED ocorreu espontaneamente 5 . Alguns casos de HED espontâneo têm sido relatados, associados a doenças infecciosas (sinusites e otite média aguda) 5-11 , malformações vasculares da dura-máter 5,12,13 , distúrbios da coagulação 14,15 e metástases na calota craniana 16 . Neste artigo apresentamos dois casos de HED espontâneo, um deles associado a distúrbios da coagulação e o outro a pansinusite. Aspectos etiológicos dos HED espontâneos são discutidos. RELATO DOS CASOSCaso 1 -LA, 12 anos, sexo feminino, com insuficiência renal crônica devida a infecções urinárias de repetição, por bexiga neurogênica secundária a mielomeningocele corrigida no primeiro dia de vida. Foi submetida a transplante renal, houve moderada perda sanguínea, recebendo cerca de 400 ml de concentrado de hemácias no intra-operatório. Após o transplante foi mantida em UTI; no 3º dia pós-operatório, sem qualquer história de trauma, tornou-se irritadiça com cefaléia intensa na região parietal direita.

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Changes in blood coagulation and fibrinolysis during the postoperative period

Cited by 116 publications

References 25 publications

Hemostatic Changes Following Surgery

Hemostatic Changes Following Surgery

Is pre-operative assessment of coagulation profile with Thrombelastography (TEG) useful in predicting venous thromboembolism (VTE) following orthopaedic surgery?

Hematoma epidural espontâneo: relato de dois casos

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