Changes in axial length after orthokeratology lens treatment for myopia: a meta-analysis

Guan, Meng; Zhao, Wei; Geng, Yu; Zhang, Yang; Ma, Jia; Chen, Zonghan; Peng, Mingqian; Li, Yan

doi:10.1007/s10792-019-01167-9

Cited by 25 publications

(35 citation statements)

References 42 publications

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“…Second, compared to emmetropic and hyperopic counterparts who demonstrated relative peripheral myopia, people with myopia displayed relative peripheral hyperopia. Orthokeratology lens could shift the relative peripheral refraction in the myopic direction [6], slow the axial elongation and thus help to delay the myopia progression [7]. However, orthokeratology lens is not appropriate for all the patients, such as patients with severe dry eye or keratitis.…”

Section: Introductionmentioning

confidence: 99%

Efficacy and safety of atropine to control myopia progression: a systematic review and meta-analysis

et al. 2020

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Background The effect and safety of atropine on delaying the progression of myopia has been extensively studied, but its optimal dose is still unclear. Therefore, the purpose of this meta-analysis is to systematically evaluate the safety and effectiveness of atropine in controlling the progression of myopia, and to explore the relationship between the dose of atropine and the effectiveness of controlling the progression of myopia. Methods This work was done through the data searched from PubMed, MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials. The Cochrane Handbook was also used to evaluate the quality of the included studies. In addition, a meta-analysis was performed using Revman5.3 software. Results A total of 10 randomized controlled trials (RCTs) were included. Myopia progression was mitigated greater in the atropine treatment group than that in the control group, with MD = − 0.80, 95% CI (− 0.94, − 0.66) during the whole observation period. There was a statistical difference among 0.05, 0.5, and 1.0% atropine (P = 0.004). In addition, less axial elongation was shown, with MD = − 0.26, 95% CI (− 0.33, − 0.18) during the whole observation period. Conclusion The effectiveness of atropine in controlling the progression of myopia was dose related. A 0.05% atropine was likely to be the optimal dose.

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Section: Introductionmentioning

confidence: 99%

Efficacy and safety of atropine to control myopia progression: a systematic review and meta-analysis

et al. 2020

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“…Second, people with myopia displayed relative peripheral hyperopia, compared to emmetropic and hyperopic counterparts who demonstrated relative peripheral myopia. Orthokeratology lens shifted the relative peripheral refraction in the myopic direction [6], slowed the axial elongation and thus helped to delay the myopia progression [7]. However, orthokeratology lens is not appropriate for all the patients and such lens are also very expensive.…”

Section: Introductionmentioning

confidence: 99%

Efficacy and Safety of Atropine to Control Myopia Progression: A Systematic Review and Meta-analysis

Zhao¹,

Cai²,

Ding

et al. 2020

Preprint

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Background: The effect and safety of atropine on delaying the progression of myopia has been extensively studied, but its optimal effect dose is still unclear. Therefore, the purpose of this meta-analysis is to systematically evaluate the safety and effectiveness of atropine in controlling the progression of myopia, and to explore the relationship between the dose of atropine and the effect of controlling the progression of myopia. Methods: This work was done through the data search from PubMed, MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials. The Cochrane Handbook was also used to evaluate the quality of these included studies. In addition, a meta-analysis was performed using Revman5.3 software. Results: A total of 10 randomized controlled trials (RCTs) were included. Myopia progression was mitigated greater in the atropine treatment group than the control group, with MD = -0.80, 95% CI (-0.94, -0.66) during the whole observation period. There was a statistical difference between 0.05%, 0.5%, and 1.0% atropine (P = 0.004). In addition, less axial elongation was showed, with MD = -0.26, 95% CI (-0.33, -0.18) during the whole observation period. Conclusion: The effect of atropine in controlling the progression of myopia was dose related. A 0.05% atropine was likely to be the optimal dose.

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“…[7][8][9] The prevalence of myopia has increased worldwide, and it is a global public health problem. 10,11 It is estimated that by 2050 half of the world's population will have myopia. 1,12 It is important that progression of myopia is controlled to reduce the incidence of other detrimental eye conditions later on.…”

Section: Context and Policy Issuesmentioning

confidence: 99%

Lenses and Spectacles to Prevent Myopia Worsening in Children

Banerjee¹,

Horton²

2021

cjht

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A total of 5 relevant systematic reviews and 7 randomized controlled trials (RCTs) were identified. Myopia progression and axial length elongation was less with omafilcon A (MiSight) contact lenses compared to single-vision lenses (1 RCT; statistical significance of difference was not reported). Myopia progression and axial length elongation was less with defocus incorporated multiple segments spectacle lenses compared to single-vision spectacle lenses (1 RCT; the between-group difference was statistically significant). Myopia progression was less with orthokeratology contact lenses compared to single-vision contact lenses or single-vision lenses (2 systematic reviews and 2 RCTs; between-group difference was statistically significant or statistical significance was not reported) and axial length elongation was less (5 systematic reviews and 2 RCTs; between-group difference was statistically significant or statistical significance was not reported). Myopia progression and axial length elongation was less with multifocal lenses compared with single-vision contact lenses (1 systematic review and 2 RCTs; between-group difference was statistically significant). Findings need to be interpreted in the light of limitations, such as limited quantity and quality of the included primary studies, limited information regarding adverse events, and lack of long-term data. No economic evaluations reporting on the cost-effectiveness of these interventions were identified.

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Changes in axial length after orthokeratology lens treatment for myopia: a meta-analysis

Cited by 25 publications

References 42 publications

Efficacy and safety of atropine to control myopia progression: a systematic review and meta-analysis

Efficacy and safety of atropine to control myopia progression: a systematic review and meta-analysis

Efficacy and Safety of Atropine to Control Myopia Progression: A Systematic Review and Meta-analysis

Lenses and Spectacles to Prevent Myopia Worsening in Children

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