Changes in acromegaly comorbidities, treatment, and outcome over three decades: a nationwide cohort study
Christian Rosendal,
Mai Christiansen Arlien-Søborg,
Eigil Husted Nielsen
et al.
Abstract:ObjectiveTo study the time-dependent changes in disease features of Danish patients with acromegaly, including treatment modalities, biochemical outcome, and comorbidities, with a particular focus on cancer and mortality.MethodsPertinent acromegaly-related variables were collected from 739 patients diagnosed since 1990. Data are presented across three decades (1990–1999, 2000–2009, and 2010–2021) based on the year of diagnosis or treatment initiation.ResultsAdenoma size and insulin-like growth factor I (IGF-I)… Show more
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