Abstract:Differential scanning calorimetry
(DSC) of dipalmitoyl phosphatidylcholine
(DPPC), dihexanoyl phosphatidylcholine, and dipalmitoyl phosphatidylglycerol
bicelles reveals two endothermic peaks. Based on analysis of small
angle neutron scattering and small angle X-ray scattering data, the
two DSC peaks are associated with the melting of DPPC and a change
in bicellar morphologynamely, either bicelle-to-spherical
vesicle or oblate-to-spherical vesicle. The reversibility of the two
structural transformations was ex… Show more
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