Changes and significance of plasma fibrinogen gamma‐chain concentration in preeclampsia patients

Zhu, Yuli; Tan, YunChang; Liang, XiaoJun; OuYang, LiangLiang; Wang, YouNv; Longyi, Tan; Shen, Chao; Xu, Wei; Hu, Zhijian; Zhou, HuiXiang

doi:10.1002/jcla.23704

Cited by 1 publication

(1 citation statement)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Duan et al found that fibrinogen in mild preeclampsia patients was not less than in controls, and fibrinogen in severe preeclampsia patients was significantly higher than in controls [ 3 ]. Another research demonstrated that at the gestational age of 32 weeks, the plasma fibrinogen γ chain levels in preeclampsia patients were significantly elevated [ 13 ]. However, Chen and her colleagues concluded that the fibrinogen concentration in preeclampsia patients was significantly lower than in healthy pregnant women (1.59 ± 1.07 versus 4.19 ± 0.63, p < 0.0001).…”

Section: Discussionmentioning

confidence: 99%

Preeclampsia complicated with hypofibrinogenemia: 2 case reports and review of the literature

Li,

Jin,

Gong

et al. 2023

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

Background Preeclampsia complicated with hypofibrinogenemia is a rare disorder. We report two cases of severe preeclampsia complicated with hypofibrinogenemia followed by postpartum haemorrhage (PPH). Case Two women diagnosed as preeclampsia and hypofibrinogenemia developed severe PPH after undergoing Cesarean sections. Besides supplement with fibrinogen concentrate and supportive treatment, the second patient got administration of heparin after delivery and bleeding was stopped. The haemorrhage in case 1 didn’t disappear until an hysterectomy. The two patients both recovered and were discharged soon. Conclusions Severe preeclampsia patients with hypofibrinogenemia could suffer PPH. It’s necessary to detect and master coagulation function. Heparin could be considered to balance hypercoagulation and hypocoagulation to avoid catastrophic haemorrhage and hysterectomy.

show abstract

Section: Discussionmentioning

confidence: 99%

Preeclampsia complicated with hypofibrinogenemia: 2 case reports and review of the literature

Li,

Jin,

Gong

et al. 2023

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

show abstract

Changes and significance of plasma fibrinogen gamma‐chain concentration in preeclampsia patients

Abstract: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

Cited by 1 publication

References 10 publications

Preeclampsia complicated with hypofibrinogenemia: 2 case reports and review of the literature

Preeclampsia complicated with hypofibrinogenemia: 2 case reports and review of the literature

Contact Info

Product

Resources

About