Changes after behavior therapy among responsive and nonresponsive patients with obsessive-compulsive disorder

Yamanishi, Tomoaki; Nakaaki, Shutaro; Omori, Ichiro M; Hashimoto, Nobuhiko; Shinagawa, Yoshihiro; Hongo, Jin; Horikoshi, Masaru; Tohyama, Junko; Akechi, Tatsuo; Sawada, Tsutomu; Iidaka, Tetsuya; Furukawa, Toshi A

doi:10.1016/j.pscychresns.2008.07.004

Cited by 56 publications

(61 citation statements)

References 37 publications

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“…Indeed, it can be said that a cognitive recognition course reduces the risk of bad choices made by the addicts. This finding is consistent with previous studies, where psychotherapy, especially cognitive-behavioral therapy, improved blood flow to ventromedial prefrontal cortex, which is most closely associated with decisionmaking [12,27]. We also established that cognitive restructuring improved subjects' capability in emotion recognition from facial expressions.…”

Section: Discussionsupporting

confidence: 92%

Fast Effects of Cognitive Restructuring Training on Neurocognitive Functions in Opioid Addicts

Tavakolian¹,

Abolghasemi²

2016

Arch Psych Psych

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SummaryAim: To investigate the effect of cognitive restructuring training on neurocognitive functions related to the prefrontal cortex in opioid addicts and its relationship to relapse prevention. Method:Thirty opioid addicts who completed a 21-day detoxification program were randomly placed in experimental and control groups. Before and after the training, the subjects underwent urinalysis and were tested on the Addiction-Stroop Task, Iowa Gambling Task, Wisconsin Card Sorting test and Emotion Recognition Scale.Results: Decision-making and emotion recognition were improved after the training course, but no significant difference was observed in attention bias, cognitive flexibility and relapse. Conclusions:Cognitive restructuring training and improvement of some neuropsychological functions are not enough to prevent relapse, and attention bias and cognitive flexibility should be adjusted.cognitive restructuring/neurocognitive function/addiction/relapse

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Section: Discussionsupporting

confidence: 92%

Fast Effects of Cognitive Restructuring Training on Neurocognitive Functions in Opioid Addicts

Tavakolian¹,

Abolghasemi²

2016

Arch Psych Psych

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“…The existence of a potential impairment of the visual system while processing triggers of the appetitive system was already suggested in a study by Olatunji et al (2011) in which patients with OCD revealed difficulties in disengaging from erotic images during an emotional attentional blink paradigm. Interestingly, Yamanishi et al (2009) reported that increased regional cerebral blood flow in visual regions (e.g., fusiform gyrus; angular gyrus) was associated with good therapeutic response in OCD patients.…”

Section: Discussionmentioning

confidence: 99%

“…Additionally, functional neuroimaging studies demonstrate that the provocation of OCD symptoms is associated with an activation of the orbitofrontal and anterior cingulated loops (Rotge et al 2008). Effective therapy tends to normalize the hyper activation of these frontal-subcortical pathways as well as increasing the activity of secondary visual regions (e.g., fusiform gyrus) (Yamanishi et al 2009). …”

Section: Introductionmentioning

confidence: 99%

Brain activation of the defensive and appetitive survival systems in obsessive compulsive disorder

Gonçalves

Soares

Carvalho

et al. 2014

Brain Imaging and Behavior

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Several studies have shown that basic emotions are responsible for a significant enhancement of early visual processes and increased activation in visual processing brain regions. It may be possible that the cognitive uncertainty and repeated behavioral checking evident in Obsessive Compulsive Disorder (OCD) is due to the existence of abnormalities in basic survival circuits, particularly those associated with the visual processing of the physical characteristics of emotional-laden stimuli. The objective of the present study was to test if patients with OCD show evidence of altered basic survival circuits, particularly those associated with the visual processing of the physical characteristics of emotional stimuli. Fifteen patients with OCD and 12 healthy controls underwent functional magnetic resonance imaging acquisition while being exposed to emotional pictures, with different levels of arousal, intended to trigger the defensive and appetitive basic survival circuits. Overall, the present results seem to indicate dissociation in the activity of the defense and appetitive survival systems in OCD. Results suggest that the clinical group reacts to basic threat with a strong activation of the defensive system mobilizing widespread brain networks (i.e., frontal, temporal, occipital-parietal, and subcortical nucleus) and blocking the activation of the appetitive system when facing positive emotional triggers from the initial stages of visual processing (i.e., superior occipital gyrus).

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“…These results were further substantiated in a subsequent study (Schwartz et al 1996). The involvement of the basal ganglia, especially the caudatus, and the orbital and medial prefrontal cortex in changes after therapy found broad confirmation in a second series of studies (Freyer et al 2011;Nabeyama et al 2008;Nakao et al 2005;Nakatani et al 2003;Saxena et al 2009;Yamanishi et al 2009). Considerable evidence from other studies implicates these structures in obsessive--compulsive disorder (Whiteside et al 2004), suggesting that OCD symptoms are mediated by hyperactivity in orbitofrontal-subcortical circuit, which normalises in symptomatic remission after therapy (Saxena et al 2001).…”

Section: Obsessive-compulsive Disordermentioning

confidence: 66%

Psychotherapy Outcome Research and Neuroimaging

Viviani

Nagl

Buchheim

2014

Psychotherapy Research

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Changes after behavior therapy among responsive and nonresponsive patients with obsessive-compulsive disorder

Cited by 56 publications

References 37 publications

Fast Effects of Cognitive Restructuring Training on Neurocognitive Functions in Opioid Addicts

Fast Effects of Cognitive Restructuring Training on Neurocognitive Functions in Opioid Addicts

Brain activation of the defensive and appetitive survival systems in obsessive compulsive disorder

Psychotherapy Outcome Research and Neuroimaging

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