The aim of this article is to establish the specialization method on characteristic ideals for finitely generated torsion modules over a complete local normal domain R that is module-where O is the ring of integers of a finite extension of the field of p-adic integers Qp. The specialization method is a technique that recovers the information on the characteristic ideal charR(M ) from char R/I (M/IM ), where I varies in a certain family of nonzero principal ideals of R. As applications, we prove Euler system bound over Cohen-Macaulay normal domains by combining the main results in [31] and then we prove one of divisibilities of the Iwasawa main conjecture for two-variable Hida deformations generalizing the main theorem obtained in [28].