Clinacanthus nutans (C. nutans) herb is one of the medicinal herbal species from Acanthaceae family. This plant is native to tropical and subtropical Asian regions. It is mostly cultivated in Malaysia, Thailand, and Indonesia. In Thailand, C. nutans was initially invented as an antiviral cream and clinically proven to treat herpes simplex virus (HSV) and varicella-zoster virus (VZS) infections (Charuwichitrat et al., 1996;Jayavasu et al., 1992;Sangkitporn et al., 1995). The cream also exhibited anti-dengue property. Another vital medicinal benefit of the C. nutans herb is as an anticancer. Numerous studies have revealed the cytotoxicity and antiproliferative effects of C. nutans extract against various human cancer cell lines such as