Change in subfoveal choroidal thickness in central serous chorioretinopathy following spontaneous resolution and low-fluence photodynamic therapy

Kang, Na Hee; Yt, Kim

doi:10.1038/eye.2012.273

Cited by 50 publications

(44 citation statements)

References 27 publications

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“…The choroidal leakage and thickness were shown to be decreased after PDT in patients with polypoidal choroidal vasculopathy and CSC. 5,10 Kang and Kim 11 reported that the subfoveal choroidal thickness was decreased in both spontaneously resolved and PDT-treated CSC patients. However, the amount of decrease was higher in PDT-treated patients.…”

Section: Introductionmentioning

confidence: 99%

The time of resolution and the rate of recurrence in acute central serous chorioretinopathy following spontaneous resolution and low-fluence photodynamic therapy: a case–control study

Özkaya

Alkın

Özveren

et al. 2016

Eye

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Purpose To evaluate the resolution time and the recurrence rate of acute central serous chorioretinopathy (CSC) after spontaneous resolution and low-fluence photodynamic therapy (PDT). Methods Case-control study: The CSC patients who were admitted to our clinic for the first time were included. No treatment was given during the first 6 months. Patients were treated with PDT after 6 months from the initial signs of the disease, if they did not show any sign of resolution. The patients who showed a significant decrease in subretinal fluid after month 6 were not scheduled for PDT. The primary outcomes were the resolution time and the recurrence rate after the first episode. Secondary outcome measures were the change in BCVA and CRT during the follow up. Results A total of 77 consecutive eyes of 77 patients were included, 41 eyes (53.2%) with spontaneously resolved CSC and 36 eyes (46.8%) with PDT-treated CSC. The initial resolution time was 4.1 ± 3.2 months in spontaneous resolution group, and 8.1 ± 0.8 months in PDT group, respectively (Po0.001). The recurrence rate was 51.2% in spontaneous resolution group, and 25% in PDT group (P = 0.01). The change in BCVA from baseline to the last follow-up visit was statistically significant in both groups (P = 0.002, P = 0.003, respectively). The change in CRT from baseline to the last follow up was also statistically significant in both groups (P = 0.002, P = 0.003, respectively). Conclusions The recurrence rate of acute CSC was lower in PDT-treated patients than the spontaneously resolved patients.

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Section: Introductionmentioning

confidence: 99%

The time of resolution and the rate of recurrence in acute central serous chorioretinopathy following spontaneous resolution and low-fluence photodynamic therapy: a case–control study

Özkaya

Alkın

Özveren

et al. 2016

Eye

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“…Choroidal thickness has been investigated in healthy individuals, patients with high myopia, polypoidal choroidal vasculopathy, age-related macular degeneration, central serous chorioretinopathy, glaucoma, pseudoexfoliation syndrome, sarcoid, tuberculosis-related granulomatous uveitis, and Behcet diseaserelated posterior uveitis. [8][9][10][11][12][13][14][15] Investigation of choroidal morphology in patients with scleroderma may help better understanding of choroidal involvement in patients with scleroderma. The aim of the present study was to investigate the choroidal thickness in patients with scleroderma and to compare them with healthy control subjects.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of choroidal thickness in patients with scleroderma

Coşkun

Zengin

Kenan

et al. 2016

Eye

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Purpose To investigate the choroidal thickness in patients with scleroderma and to compare them with healthy control subjects. Methods Forty-six patients with scleroderma (3 male and 43 female) and 31 healthy controls (6 male and 25 female) were included in the study. Twenty-five patients had limited-type and 21 patients had diffuse-type scleroderma. Only left eyes of the patients and control subjects were used in the analysis. Demographic features of all the patients and control subjects were recorded. Each subject underwent ophthalmological examinations including refraction, visual acuity, intraocular pressure, axial length (AXL) measurement, slit-lamp biomicroscopy, and fundus examination. Body mass index (BMI) was estimated for all participants. Results There were no significant differences between the patients with scleroderma and the control subjects in terms of age, gender, BMI, mean AXL, and mean spherical equivalent refractive error (SE) (P = 0.1, P = 0.086, P = 0.37, P = 0.55, and P = 0.072 respectively). The patients with scleroderma had significantly thinner nasal, temporal, and subfoveal choroid than the healthy control subjects (P 1 = 0.012, P 2 = 0.046, and P 3 o0.001, respectively). There were no significant differences between the patients with limited-type and diffuse-type scleroderma in terms of age, gender, BMI, mean AXL, mean SE, nasal, temporal, and subfoveal choroidal thicknesses (all P40.05). Conclusions Choroidal thickness in patients with scleroderma was significantly less than healthy control subjects. Vasculopathy in scleroderma is characterized by obliteration of arterioles and reduced capillary density may cause atrophy of choroid in patients with scleroderma.

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“…Currently, the EDI-OCT technique is accepted as a useful tool to study the morphologic changes associated with many choroidal disorders. [8][9][10][11][18][19][20][21][22][23] Decreased choroidal thickness has been observed in age-related macular degeneration, 19 glaucoma, 20 and high myopia. 9 Increased choroidal thickness has been observed in central serous chorioretinopathy, 20 polypoidal choroidal vasculopathy, 21 and choroidal neovascularization.…”

Section: Discussionmentioning

confidence: 98%

The Effect of Systemic Tamsulosin Hydrochloride on Choroidal Thickness Measured by Enhanced Depth Imaging Spectral Domain Optical Coherence Tomography

Sarı¹,

Yazıcı²,

Koç³

et al. 2014

Current Eye Research

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Tamsulosin causes a significant increase in EDI-OCT-based choroidal thickness measurements. This increase might be associated with choroidal vasodilation in consequence of blockade of sympathetic α1A-adrenoceptors, which is critical for the maintenance of vascular tone and resistance in the choroidal vascular architecture. This should be kept in mind when choroidal disease and its response to treatment are followed by EDI-OCT imaging.

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Change in subfoveal choroidal thickness in central serous chorioretinopathy following spontaneous resolution and low-fluence photodynamic therapy

Cited by 50 publications

References 27 publications

The time of resolution and the rate of recurrence in acute central serous chorioretinopathy following spontaneous resolution and low-fluence photodynamic therapy: a case–control study

The time of resolution and the rate of recurrence in acute central serous chorioretinopathy following spontaneous resolution and low-fluence photodynamic therapy: a case–control study

Evaluation of choroidal thickness in patients with scleroderma

The Effect of Systemic Tamsulosin Hydrochloride on Choroidal Thickness Measured by Enhanced Depth Imaging Spectral Domain Optical Coherence Tomography

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