Change in levels of cyclic AMP and cyclic GMP during pregnancy and larval development of the tsetse fly, Glossina morsitans

Denlinger, David L.; Gnagey, A.L.; Rockey, Sarah J.; Chaudhury, M. F. B.; Fertel, Richard H.

doi:10.1016/0742-8413(84)90006-9

Cited by 3 publications

(3 citation statements)

References 19 publications

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“…This could be due to a reduction in the amounts of free nutrients available to trypanosomes which will instead go towards larval production while levels of circulating hormones will also be different in pregnant tsetse. Although levels of cyclic nucleotides fluctuate during pregnancy in tsetse [24] feeding of 8-Br-cGMP or 8-Br-cAMP had no effect on maturation rates [12].…”

Section: Discussionmentioning

confidence: 99%

Factors Affecting Trypanosome Maturation in Tsetse Flies

et al. 2007

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Trypanosoma brucei brucei infections which establish successfully in the tsetse fly midgut may subsequently mature into mammalian infective trypanosomes in the salivary glands. This maturation is not automatic and the control of these events is complex. Utilising direct in vivo feeding experiments, we report maturation of T. b. brucei infections in tsetse is regulated by antioxidants as well as environmental stimuli. Dissection of the maturation process provides opportunities to develop transmission blocking vaccines for trypanosomiasis. The present work suggests L-cysteine and/or nitric oxide are necessary for the differentiation of trypanosome midgut infections in tsetse.

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Section: Discussionmentioning

confidence: 99%

Factors Affecting Trypanosome Maturation in Tsetse Flies

et al. 2007

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“…Such a factor might very well be the initiator of the rhythmic pulses ) that precede parturition. Cyclic AMP is a likely mediator of this response: an injection of dibutryl cyclic AMP or cholera toxin, an activator of adenylate cyclase, causes premature parturition (abortion) (Denlinger et al, 1978) and concentrations of cyclic AMP are elevated in both the female and larva at parturition (Denlinger et al, 1984). Attempts to stimulate parturition with several of the myotropic neruropeptides isolated from other insects have thus far failed (our unpublished observations).…”

Section: Neural and Hormonal Control Of Parturitionmentioning

confidence: 92%

Metamorphosis behaviour and regulation in tsetse flies (Glossinaspp.) (Diptera: Glossinidae): a review

Žďárek

Denlinger

1993

Bull. Entomol. Res.

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This review examines the recent literature on tsetse (Glossina spp.) metamorphosis behaviour and its regulation. The behavioural events associated with metamorphosis are highly specific and most occur only once during the life of the fly. The review begins with the larva's commitment to metamorphosis and then discusses the behaviour associated with parturition, wandering of the third instar larva, pupariation, pupation and adult eclosion. While certain aspects of tsetse metamorphosis behaviour are common to the higher Diptera, the peculiar reproductive strategy of tsetse has dictated many modifications. Most notable of the tsetse peculiarities are the larva's late commitment to metamorphosis, the contribution by the mother in deciding the onset of the wandering period, the brevity of the wandering period, the involvement of the nervous system in co-ordinating puparial tanning, the tight packaging of the pupa within the puparium, the long duration of pharate adult development, and the great expansion of the body that occurs following eclosion. A final section discusses the potential for disrupting tsetse metamorphosis. IntroductionThis review examines the behavioural events associated with metamorphosis in tsetse (Glossina spp.) and discusses the regulation of these activities by the endocrine and nervous systems. Successful metamorphosis requires the performance of sets of behaviours that are developmentally specific and must be executed with precision and in the proper sequence. We start with the third instar larva's commitment to metamorphosis and then discuss the subsequent sequence of events that includes parturition, wandering behaviour, pupariation, intrapuparial behaviour, and finally adult eclosion. Though other reviews provide a more general survey of Diptera metamorphosis behaviour (Zdarek, 1985; Denlinger & Zdarek, in press), tsetse, in many respects, do not fit the pattern of other flies. For example, corn-

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“…Hemolymphatic determinations indicate that cAMP titer undergoes changes at parturition in Glossina (Denlinger et al, 1984). Injections of cAMP @enlinger et Robert et al.…”

Section: Cyclic Amp Activitymentioning

confidence: 99%

Regulation of last reproduction steps in tsetse flies (Glossina:Diptera)

Grillot

Raabe²

1989

Invertebrate Reproduction & Development

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and 2Newoendocrinologie des Znsectes, CNRS UA 669, Universitt! P. and M. Curie, 12, rue Cuvier, 75252 Paris Ckdex 05, FranceThe regulation of ovulation and parturition, in the viviparous tsetse flies, constitutes a very pncisely adjusted mechanism. Indeed the process of vitekgenesis takes places, in one oocyte only, during the incubation period when the larva is nourished in utero on milk produced by the mother. Neuropeptides, biogenic amines, neurotransmitters as well as ecdysone, and 20-hydroxyecdysone and also nervous outputs regulate ovulation and pturition A model is proposed for the mechanisms controlling these processes.

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Change in levels of cyclic AMP and cyclic GMP during pregnancy and larval development of the tsetse fly, Glossina morsitans

Cited by 3 publications

References 19 publications

Factors Affecting Trypanosome Maturation in Tsetse Flies

Factors Affecting Trypanosome Maturation in Tsetse Flies

Metamorphosis behaviour and regulation in tsetse flies (Glossinaspp.) (Diptera: Glossinidae): a review

Regulation of last reproduction steps in tsetse flies (Glossina:Diptera)

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