Change in corneal microstructure with rigid gas permeable contact lens use following collagen cross-linking: an in vivo confocal microscopy study

Sehra, Sri Vatsa; Titiyal, Jeewan S; Sharma, Namrata; Tandon, Radhika; Sinha, Rajesh

doi:10.1136/bjophthalmol-2013-303934

Cited by 10 publications

(4 citation statements)

References 27 publications

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“…Immediate use of RGPCLs after corneal crosslinking (CXL) might delay sub-basal nerve plexus regeneration and cause epithelial cell stress [ 85 ]. Ünlü et al reported better tolerance to RGPCLs for at least six months after CXL, probably caused by a decreased corneal sensitivity and flattening of the cornea [ 86 ].…”

Section: Resultsmentioning

confidence: 99%

Nonsurgical Procedures for Keratoconus Management

Rico-del-Viejo

García-Montero

Hernández-Verdejo

et al. 2017

Journal of Ophthalmology

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Objectives To describe the past 20 years' correction modalities for keratoconus and their visual outcomes and possible complications. Methods A review of the published literature related to the visual outcomes and possible complications in the context of keratoconus management using nonsurgical procedures for the last 20 years (glasses and contact lenses) was performed. Original articles that reported the outcome of any correction modalities of keratoconus management were reviewed. Results The most nonsurgical procedure used on keratoconus management is the contact lens fitting. Soft contact lenses and soft toric contact lenses, rigid gas-permeable contact lenses, piggyback contact lens system, hybrid contact lenses, and scleral and corneoscleral contact lenses form the contemporary range of available lens types for keratoconus management with contact lenses. All of them try to restore the vision, improve the quality of life, and delay surgical procedures in patients with this disease. Complications are derived from the intolerance of using contact lens, and the use of each depends on keratoconus severity. Conclusions In the context of nonsurgical procedures, the use of contact lenses for the management of keratoconic patients represents a good alternative to restore vision and improve the quality of live in this population.

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Section: Resultsmentioning

confidence: 99%

Nonsurgical Procedures for Keratoconus Management

Rico-del-Viejo

García-Montero

Hernández-Verdejo

et al. 2017

Journal of Ophthalmology

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“…The current study also found that CXL surgery did not increase compliance with RGPCL wear. Previous studies have shown that RGPCL wear post-CXL was relatively well tolerated due to the decreased corneal sensitivity and the flattening effect of CXL [11,20,21]. Unlu et al [11] also found that the mean duration of RGPCL wear increased after CXL surgery.…”

Section: Discussionmentioning

confidence: 98%

Factors Affecting Long-Term Compliance with Rigid Gas-Permeable Contact Lens Wear in Patients with Keratoconus

Xue

Zhou

Chen

et al. 2022

JCM

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The purpose of the study was to investigate the factors affecting long-term compliance with rigid gas-permeable contact lens (RGPCL) wear in patients with keratoconus (KC). A total of 189 patients with KC (374 eyes) were included in the study, and were divided into two groups: the compliant group and the non-compliant group. Corneal topographic measurements, refractive results, and RGPCL parameters were compared between the two groups. A vision-related quality of life questionnaire was completed by all of the patients. The results demonstrated that patients diagnosed with bilateral KC were more compliant with RGPCL wear than patients diagnosed with unilateral KC (p = 0.0167). There were no significant differences between the compliant and non-compliant groups in terms of their corneal topographic measurements, refractive results, RGPCL parameters, or corneal cross-linking surgery history (all p > 0.05). In contrast, KC patients’ subjective experience with RGPCL wear—including visual acuity (p = 0.006), overall satisfaction (p < 0.001), quality of life (p < 0.001), and good adaptation during the short-term (p < 0.001)—had a significant effect on the long-term compliance with RGPCL wear. In conclusion, patients’ subjective experiences, rather than their ocular biometrics, significantly influence their long-term compliance with RGPCL wear.

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“…Our study could not evaluate the corneal sensitivity's recovery to chemical and temperature stimuli. We started fitting RGP lenses one month post‐CXL, while previous authors have fitted RGP lenses as soon as the epithelial defect has healed, as early as one week after CXL . Given the fact that RGP lenses affect the corneal healing process after CXL, the ideal time for fitting RGP lenses post‐CXL remains uncertain.…”

Section: Discussionmentioning

confidence: 99%