The districts of Samara region are characterized by specific combination of orographic structure, hydrological regimes, soil and vegetation cover features, combined with a high level of anthropogenic pressure. The revealing of negative changes associated with the anthropogenic exploitation regimes incliding salinization and waterlogging after irrigation, soil erosion, transformation of non-cultivated fields into deposits, overgrowing of old quarries etc. seems to be a difficult task when carrying out by ground-based studies related to a large-scale land resources of the region. The use of remote sensing data, resulted by a time series of images for the same territory, opens up wide opportunities, on condition that the regional ground-based standardization is carried out.