Challenges of the Intraocular Pressure Measurements in the Keratitis

Abstract

The maintenance of the aqueous humor circulation is vital for nourishing the anterior segment structures and maintaining the shape of the eyeball. Imbalances in the production and drainage of aqueous humor are well-known occurrences during inflammatory processes in the anterior chamber, with keratitis being a major contributor. Elevated intraocular pressure (IOP) is a common complication during active microbial keratitis. However, even under normal conditions, corneal biomechanical properties, thickness, and curvature can complicate the accuracy of IOP measurements. Ongoing research is exploring the relationship between corneal characteristics and IOP. Corneal conditions related to keratitis, such as band-keratopathy, corneal edema, astigmatism, and corneal ectatic disorders, pose significant challenges for managing high-pressure-related complications. Different IOP measurement techniques may be preferable in various corneal prominent conditions. Regular IOP checks are necessary to avoid possible optic nerve damage during keratitis treatment. It is crucial to select the appropriate measurement technique and consider potential over- and underestimations of IOP due to corneal disorders.