“…Table 4 summarizes the retrospective and prospective series on chemoradiation in locally advanced NSCLC from India. Studies by Shrimali et al 24 and Kapoor et al 25 addressed the challenges of delivery of radical chemoradiation in stage III NSCLC with respect to spatial location of tumor and burden of disease. Volumetric-modulated arc therapy is preferred over three-dimensional conformal radiotherapy in patients with bulky central disease so that dose to target volume is not compromised and organs at risk constraints are met.…”