Challenges in Translating Regenerative Therapies for Spinal Cord Injury
Andrew N. Stewart,
John C. Gensel,
Linda Jones
et al.
Abstract:Regenerating the injured spinal cord is a substantial challenge with many obstacles that need to be overcome to achieve robust functional benefits. This abundance of hurdles can partly explain the limited success when applying regenerative intervention treatments in animal models and/or people. In this article, we elaborate on a few of these obstacles, starting with the applicability of animal models and how they compare to the clinical setting. We then discuss the requirement for combinatorial interventions a… Show more
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