Challenges in developing medicinal plant databases for sharing ethnopharmacological knowledge

Ningthoujam, Sanjoy Singh; Talukdar, Anupam Das; Potsangbam, Kumar Singh; Choudhury, Manabendra Dutta

doi:10.1016/j.jep.2012.02.042

Cited by 60 publications

(36 citation statements)

References 151 publications

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“…These documents therefore can be viewed as legal tools to foster protection of the rights of the communities. These databases are useful for exemplifying the value of encouraging the development and improvement of community knowledge registers and biocultural protocols, and linking them with national databases for protection (Ningthoujam et al, 2012).…”

Section: Medicinal and Aromatic Plants And Human Welfarementioning

confidence: 99%

Conservation and sustainable uses of medicinal and aromatic plants genetic resources on the worldwide for human welfare

Barata

Rocha

Lopes

et al. 2016

Industrial Crops and Products

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a b s t r a c tPlants have been used since ancient times to heal and cure diseases and to improve the health and the wellbeing of the populations. Medicinal and aromatic plants still form the basis of traditional or indigenous health systems of the populations in most of the developing countries, as reported by the World Health Organization (WHO).As a result of the expanding interest in medicinal and aromatic plants, new income generating opportunities are opening up for rural populations. With many of the MAPs gathered from the wild, the recollection and sale of MAPs is providing a complementary source of income for many poor rural households.Currently, we are facing an incomparably growing pressure on plant populations in the wild due to the increasing commercial recollection, largely unmonitored trade, and habitat loss. Profound knowledge of the features of the (international) trade in botanicals (size, structure, streams, commodities, traded quantities and their origin) is (1) essential for assessing the trade's impact on the plant populations concerned; and (2) required for conservation concepts and measures which have to meet future supply and the provisions of species conservation.

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Section: Medicinal and Aromatic Plants And Human Welfarementioning

confidence: 99%

Conservation and sustainable uses of medicinal and aromatic plants genetic resources on the worldwide for human welfare

Barata

Rocha

Lopes

et al. 2016

Industrial Crops and Products

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“…[6][7][8][9][10] The widespread use of herbal medicine comes with the risk of overdoses through inappropriate consumption. 11 Zizameleni farm (25.5717°S, 27.7959°E) specializes in the cultivation of medicinal plants.…”

Section: -5mentioning

confidence: 99%

Speciation of chromium and vanadium in medicinal plants

M¹,

Mandiwana²,

Panichev³

2016

S.Afr.j.chem.

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“…In medical systems based on herbalism, folklore, or shamanism, however, no written documents exist, and the herbal formulations used are often kept secret by the practitioners, making the information more difficult to access (Brusotti et al, 2014;Fabricant and Farnsworth, 2001). Depending on the herbs to be studied, information can be acquired from different sources, including books on medical botany (e.g., Lewis, 2003), herbals (e.g., Adams et al, 2012), review articles on medicinal plants used in a certain geographic region or by an ethnic culture (e.g., Gairola et al, 2014), field work (e.g., Kunwar et al, 2009), and computer databases (Leonti, 2011;Ningthoujam et al, 2012).…”

Section: Renewal Of the Interest In Natural Product-based Drug Discoverymentioning

confidence: 99%

Discovery and resupply of pharmacologically active plant-derived natural products: A review

2015

Draw Science

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Medicinal plants have historically proven their value as a source of molecules with therapeutic potential, and nowadays still represent an important pool for the identification of novel drug leads. In the past decades, pharmaceutical industry focused mainly on libraries of synthetic compounds as drug discovery source. They are comparably easy to produce and resupply, and demonstrate good compatibility with established high throughput screening (HTS) platforms. However, at the same time there has been a declining trend in the number of new drugs reaching the market, raising renewed scientific interest in drug discovery from natural sources, despite of its known challenges. In this survey, a brief outline of historical development is provided together with a comprehensive overview of used approaches and recent developments relevant to plant-derived natural product drug discovery. Associated challenges and major strengths of natural product- Europe PMC Funders Author ManuscriptsEurope PMC Funders Author Manuscripts based drug discovery are critically discussed. A snapshot of the advanced plant-derived natural products that are currently in actively recruiting clinical trials is also presented. Importantly, the transition of a natural compound from a "screening hit" through a "drug lead" to a "marketed drug" is associated with increasingly challenging demands for compound amount, which often cannot be met by re-isolation from the respective plant sources. In this regard, existing alternatives for resupply are also discussed, including different biotechnology approaches and total organic synthesis.While the intrinsic complexity of natural product-based drug discovery necessitates highly integrated interdisciplinary approaches, the reviewed scientific developments, recent technological advances, and research trends clearly indicate that natural products will be among the most important sources of new drugs also in the future.

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Challenges in developing medicinal plant databases for sharing ethnopharmacological knowledge

Cited by 60 publications

References 151 publications

Conservation and sustainable uses of medicinal and aromatic plants genetic resources on the worldwide for human welfare

Conservation and sustainable uses of medicinal and aromatic plants genetic resources on the worldwide for human welfare

Speciation of chromium and vanadium in medicinal plants

Discovery and resupply of pharmacologically active plant-derived natural products: A review

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