2020
DOI: 10.5935/0103-507x.20200075
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Abstract: The COVID-19 pandemic has brought concerns to managers, healthcare professionals, and the general population related to the potential mechanical ventilators’ shortage for severely ill patients. In Brazil, there are several initiatives aimed at producing alternative ventilators to cover this gap. To assist the teams that work in these initiatives, we provide a discussion of some basic concepts on physiology and respiratory mechanics, commonly used mechanical ventilation terms, the differences between triggering… Show more

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Cited by 5 publications
(5 citation statements)
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“…Mortality appeared to have decreased significantly in patients with diabetes (19% vs 43%) and arterial hypertension (8 vs 26%). The rapid progression of the disease correlated with the radiological scene of pneumonia when the groundglass phase (days 1-6) transforms into the reticulation phase (7)(8)(9)(10)(11)(12)(13)(14). Early treatment with CPAP was also described in other studies [6,7] as well as in editorial letters [8].…”
Section: Introductionmentioning
confidence: 80%
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“…Mortality appeared to have decreased significantly in patients with diabetes (19% vs 43%) and arterial hypertension (8 vs 26%). The rapid progression of the disease correlated with the radiological scene of pneumonia when the groundglass phase (days 1-6) transforms into the reticulation phase (7)(8)(9)(10)(11)(12)(13)(14). Early treatment with CPAP was also described in other studies [6,7] as well as in editorial letters [8].…”
Section: Introductionmentioning
confidence: 80%
“…Industrial enterprises and scientists also tried to succeed in development of low-cost ventilators [11][12][13][14][15]. Despite the fact that Garmendia et al [16] designed and clinically tested even much cheaper CPAP machines proposing 70-80 EUR instead of 600 EUR, the next study shows that early CPAP intervention could result in a potentially viable treatment option for patients only during the first days of hospitalisation [17].…”
Section: Discussionmentioning
confidence: 99%
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“…Industrial enterprises and scientists also tried to succeed in development of low-cost ventilators [11][12][13][14][15]. Despite the fact that Garmendia et al [16] designed and clinically tested even much cheaper CPAP machines proposing 70-80 EUR instead of 600 EUR, the next study shows that early CPAP intervention could result in a potentially viable treatment option for patients only during the rst days of hospitalisation [17].…”
Section: Not Requiredmentioning
confidence: 99%
“…The statistical analysis of E% was not conducted due to the fact that this parameter was derived from AE. According to the ANVISA, the manufacturers have to present clinical and laboratory trials (SUZUMURA et al, 2020 This study has begun due to the unexpected findings in CMV-PC pressure signals from commercial and prototype lung ventilators that were recorded for maintenance and assessment at the node IPT-POLI. These findings highlighted gaps in the standard that allow different waveform shapes to comply with standard requirements.…”
Section: E%mentioning
confidence: 99%