Challenges Associated with the Effective Management of HIV Infection in a Low Income Setting in Sub Saharan Africa: Case Study of Nigeria

Erhabor, O; Ejele, Oseikhuemen Adebayo; Nwauche, CA; Akani, Chris; Cosmos, Eyindah; Allagoa, Dennis O.; Alikor, A D Edward; Aaron, Cohen; Opurum, Hamilton; Obunge, Orikomaba; Babatunde, Seye; Frank-Peterside, Nnenna; Chinenye, S; Anele, Ihekwaba E.; Adias, Teddy Charles; Uko, Emmanuel Kufre; Dennis, Edward A.; Buseri, I Fiekumo; Jeremiah, Zacheus Awortu; Confidence, Wachuckwu; Obioma, Azuonwu; Abbey, Samuel Douglas; Frank, Onwuka; Ebitimi, N Etebu; Seleye–Fubara, D; Humphrey, Osadolor

doi:10.5772/19500

Cited by 2 publications

(3 citation statements)

References 64 publications

(43 reference statements)

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“…The HIV/AIDS epidemic has already devastated Nigeria, with nearly a million people dead and more than two million children orphaned 5 . In unfledged and evolving countries, it has overturned several of the socio-economic, development and health improvements over three decades now as manifested among others in life anticipation at birth and infant death rate 13,17 .…”

Section: African Health Sciences Vol 15 Issue 3 September 2015mentioning

confidence: 99%

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Trends in HIV prevalence from 2008 to 2012 among young adults in Port Harcourt, Nigeria

Okonko

Nnodim

2015

Afr H. Sci.

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Background: The pandemic of HIV lines amongst the utmost infectious disease menaces in antiquity. HIV remains a problem worldwide and it's a grave health snags in developing nations particularly in Nigeria. Objective: This study focused on "trends in HIV reporting from 2008 to 2012 among young adults in Port Harcourt, Nigeria. Methods: Secondary data were collected from BMSH, Port Harcourt using a Performa specifically intended for this determination. Socio-demographic data for the subjects were recovered from coded patients' medical records kept at BMSH. The data generated was exposed to Fisher's Exact Test.

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Section: African Health Sciences Vol 15 Issue 3 September 2015mentioning

confidence: 99%

“…The epidemic of HIV lines amid the paramount infectious disease menaces in the past 1,3 . The HIV widespread lingers to be a load worldwide and offers grave public health glitches in emerging countries particularly in Nigeria 1,4,5 .…”

Section: Introductionmentioning

confidence: 99%

Trends in HIV prevalence from 2008 to 2012 among young adults in Port Harcourt, Nigeria

Okonko

Nnodim

2015

Afr H. Sci.

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“…HIV infection is a risk factor for a variety of endocrine problems [2] and throughout the world, heterosexual transmission is still the most common route of spreading HIV-1 infection [3]. Regrettably, the HIV widespread lingers to be a load worldwide and offers grave public health glitches in emerging countries particularly in Nigeria [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Body Mass Index, Blood Pressure and Serum Cortisol Level as Stress Index in Symptomatic HIV/AIDS Male Subjects on Antiretroviral Therapy Negative to Malaria Parasite in Nnewi, Anambra State, Nigeria

Ezeugwunne

Ogbodo

Analike

et al. 2019

IJCBR

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Background: HIV infection is a risk factor for a variety of endocrine problems. Objectives: This study investigated the body mass index (BMI), Systolic blood pressure (SBP), Diastolic blood pressure (DBP) and serum cortisol level as stress factor/index symptomatic HIV/AIDS male subjects on ART who are negative to malaria parasite in Nnewi, Anambra State, Nigeria. Methods: A total of 274 adult male participants aged between 18 and 60 (42 ±13) years were randomly recruited at the Voluntary Counseling and Testing (VCT) Centre in Nnamdi Azikiwe University Teaching Hospital and grouped based on WHO criteria for staging HIV into symptomatic HIV (stage 11) infected male participants on ART (A: n=69), Symptomatic HIV subjects not on ART (B: n= 69), Asymptomatic HIV positive subjects (C: n= 68) and HIV seronegative subjects (D: n= 68). Blood samples were collected from the participants for the determination of HIV status by immunochromatography and HIV confirmation by Western Blot. Enzyme-Linked Immunosorbent Assay (ELISA) was used to assay for cortisol level. Results: The results showed a significantly increased BMI and decreased mean serum cortisol level in HIV/AIDS seropositive participants on ART than in those, not on ART (p<0.05). Also, the BMI and mean serum cortisol level were significantly decreased and increased respectively in HIV/AIDS seropositive participants not on ART than in Asymptomatic HIV positive subjects and control respectively (p<0.05). However, the mean SBP and DBP did not differ significantly between the groups studied (p>0.05). Conclusion: This study revealed a decreased stress index in HIV/AIDS subjects on ART with hypercortisolism and lower BMI in symptomatic HIV participants, not on ART. Keywords: HIV; AIDS; Malaria uninfected male subjects; Cortisol; Blood pressure; Antiretroviral therapy.

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Challenges Associated with the Effective Management of HIV Infection in a Low Income Setting in Sub Saharan Africa: Case Study of Nigeria

Cited by 2 publications

References 64 publications

Trends in HIV prevalence from 2008 to 2012 among young adults in Port Harcourt, Nigeria

Trends in HIV prevalence from 2008 to 2012 among young adults in Port Harcourt, Nigeria

Body Mass Index, Blood Pressure and Serum Cortisol Level as Stress Index in Symptomatic HIV/AIDS Male Subjects on Antiretroviral Therapy Negative to Malaria Parasite in Nnewi, Anambra State, Nigeria

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