Challenges and Changes of the Breast Cancer Screening Paradigm

Cömert, Didem; Gils, Carla H. van; Veldhuis, Wouter B.; Mann, Ritse M.

doi:10.1002/jmri.28495

Cited by 4 publications

(5 citation statements)

References 134 publications

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“…52,61 Screening is a more complex and resource-intensive strategy that requires adequate capacity and infrastructure to avoid delays in diagnosis and treatment. 62 Screening programs should be undertaken only when their effectiveness has been demonstrated, when resources are sufficient to cover the target group, when facilities exist to confirm diagnoses and ensure treatment, and when the prevalence of the disease is high enough to justify the effort and costs of screening. 60,63 It should be noted that promoting early diagnosis is a necessary prerequisite to implementing population-based screening in certain situations.…”

Section: Discussionmentioning

confidence: 99%

“…73 Training is a low-cost strategy that can be used to increase knowledge of BC and BSE, reaching a large number of people with limited resources. 18,62 In terms of health prevention planning, BC awareness, education, public health, and social measures are all important. 27,52 Most people desire effective BC prevention education, which fosters healthy behaviors, not only through teaching, but also through using the breast as a model.…”

Section: Discussionmentioning

confidence: 99%

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Breast cancer awareness in reproductive women in the low- and middle-income countries: a scoping review

Nugraha Gautama,

Pimolkatekul,

Nhat Thanh

2024

Frontiers of Nursing

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Objective This study aimed to assess breast cancer (BC) awareness among reproductive women in low- and middle-income countries (LMICs), identify influencing factors, and propose feasible interventions or programs. Methods We followed a 5-step process using a modified version of Arksey and O’Malley framework methodology. A comprehensive search was conducted on the Embase, PubMed, and CINAHL electronic databases for literature published within 10 years (from 2012 to 2022). Results Thirty-three papers published between 2012 and 2020, spanning 18 countries, were included. Of these, 45.6% described a good level of knowledge, while 24.2% reported that women at reproductive ages had good awareness. Twelve influencing factors were identified in 3 categories: socio-demographic (family history, personal history, marital status, age, religion, income status, living place, and occupation), personal (self-efficacy, education, and perceived level), and external (advertisements promoting awareness). Educational programs were recommended in most (>72%) of the included studies. Conclusions While most studies reported high levels of knowledge and awareness, some found low prevalence among certain groups. Factors affecting knowledge and awareness were classified into socio-demographic, personal, and external categories, with socio-demographic factors such as age, education, income, and marital status being the most frequently cited. The studies recommended implementing educational programs, health prevention strategies, and social interventions to increase BC knowledge and awareness

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Breast cancer awareness in reproductive women in the low- and middle-income countries: a scoping review

Nugraha Gautama,

Pimolkatekul,

Nhat Thanh

2024

Frontiers of Nursing

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“…Studies investigating screening MRI performance in these risk populations reported important results, in terms of sensitivity (69%-100%) and specificity (84%-98%), as well as improved early cancer detection ($16/1000 screening examinations) and a strong reduction of interval cancers. [122][123][124] While recommendations do not count MRI as the modality of choice when screening women of average BC risk, it should be noted that these benefits seem to be independent of individualized BC risk. In support of this, a study investigating the possible utility of adjunct MRI in screening women of average risk, demonstrated high specificity (97.1%) and PPV (35.7%) in detecting BCs early in all breast density categories, while reporting 0% of interval cancers.…”

Section: Mri Techniquesmentioning

confidence: 99%

“…Acknowledging the considerable body of evidence available, some professional societies and organizations have broached the use of CE‐MRI in screening the population at intermediate BC risk, including those with extremely dense breasts (Table 2). Studies investigating screening MRI performance in these risk populations reported important results, in terms of sensitivity (69%–100%) and specificity (84%–98%), as well as improved early cancer detection (~16/1000 screening examinations) and a strong reduction of interval cancers 122–124 . While recommendations do not count MRI as the modality of choice when screening women of average BC risk, it should be noted that these benefits seem to be independent of individualized BC risk.…”

Section: Part 2: Novel Imaging Approaches Toward Risk‐adapted Breast ...mentioning

confidence: 99%

New Approaches and Recommendations for Risk‐Adapted Breast Cancer Screening

Tsarouchi

Hoxhaj

Mann

2023

Magnetic Resonance Imaging

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Population‐based breast cancer screening using mammography as the gold standard imaging modality has been in clinical practice for over 40 years. However, the limitations of mammography in terms of sensitivity and high false‐positive rates, particularly in high‐risk women, challenge the indiscriminate nature of population‐based screening. Additionally, in light of expanding research on new breast cancer risk factors, there is a growing consensus that breast cancer screening should move toward a risk‐adapted approach. Recent advancements in breast imaging technology, including contrast material‐enhanced mammography (CEM), ultrasound (US) (automated‐breast US, Doppler, elastography US), and especially magnetic resonance imaging (MRI) (abbreviated, ultrafast, and contrast‐agent free), may provide new opportunities for risk‐adapted personalized screening strategies. Moreover, the integration of artificial intelligence and radiomics techniques has the potential to enhance the performance of risk‐adapted screening. This review article summarizes the current evidence and challenges in breast cancer screening and highlights potential future perspectives for various imaging techniques in a risk‐adapted breast cancer screening approach.Evidence Level1.Technical EfficacyStage 5.

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“…Similarly, the traditional “one-size-fits-all” approach to breast cancer screening, which is based solely on the age criterion, has become obsolete because it does not take account of the biologic and epidemiologic complexity of the disease [ 9 , 10 ]. Breast cancer is the result of a complex web of causation involving multiple interacting risk factors.…”

Section: Introductionmentioning

confidence: 99%

The risk-based breast screening (RIBBS) study protocol: a personalized screening model for young women

Gennaro,

Bucchi,

Ravaioli

et al. 2024

Radiol med

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The optimal mammography screening strategy for women aged 45–49 years is a matter of debate. We present the RIBBS study protocol, a quasi-experimental, prospective, population-based study comparing a risk- and breast density-stratified screening model (interventional cohort) with annual digital mammography (DM) screening (observational control cohort) in a real-world setting. The interventional cohort consists of 10,269 women aged 45 years enrolled between 2020 and 2021 from two provinces of the Veneto Region (northen Italy). At baseline, participants underwent two-view digital breast tomosynthesis (DBT) and completed the Tyrer-Cuzick risk prediction model. Volumetric breast density (VBD) was calculated from DBT and the lifetime risk (LTR) was estimated by including VBD among the risk factors. Based on VBD and LTR, women were classified into five subgroups with specific screening protocols for subsequent screening rounds: (1) LTR ≤ 17% and nondense breast: biennial DBT; (2) LTR ≤ 17% and dense breast: biennial DBT and ultrasound; (3) LTR 17–30% or LTR > 30% without family history of BC, and nondense breast: annual DBT; (4) LTR 17–30% or > 30% without family history of BC, and dense breast: annual DBT and ultrasound; and (5) LTR > 30% and family history of BC: annual DBT and breast MRI. The interventional cohort is still ongoing. An observational, nonequivalent control cohort of 43,000 women aged 45 years participating in an annual DM screening programme was recruited in three provinces of the neighbouring Emilia-Romagna Region. Cumulative incidence rates of advanced BC at three, five, and ten years between the two cohorts will be compared, adjusting for the incidence difference at baseline.Trial registration This study is registered on Clinicaltrials.gov (NCT05675085).

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Challenges and Changes of the Breast Cancer Screening Paradigm

Cited by 4 publications

References 134 publications

Breast cancer awareness in reproductive women in the low- and middle-income countries: a scoping review

Breast cancer awareness in reproductive women in the low- and middle-income countries: a scoping review

New Approaches and Recommendations for Risk‐Adapted Breast Cancer Screening

The risk-based breast screening (RIBBS) study protocol: a personalized screening model for young women

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