Challenge of donor recruitment

Tsai, S. Lin

doi:10.1111/j.1751-2824.2009.01259.x

Cited by 2 publications

(1 citation statement)

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“…Taiwan is among the few high‐endemic countries that implement universal HBV‐NAT and HBsAg testing for its blood supply since 2013 [17]. In a previous study, a majority of Taiwanese blood donors were found to be under 30 years old [18] and according to another study, the anti‐HBc‐positive rate in this population appears to have decreased over the past 30 years due to the extensive infant vaccination programme [19]. Therefore, giving rise to the question whether Taiwan could adopt the blood donor policy for low‐endemic countries (excluding the blood donors who are anti‐HBc‐positive in order to eliminate the potential sources of occult HBV infection).…”

Section: Introductionmentioning

confidence: 99%

An economic reappraisal of hepatitis B virus testing strategy for blood donors in Taiwan

Matanhire

Lin

2020

Vox Sanguinis

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Background and objectives Taiwan is among the few hepatitis B virus (HBV) high-endemic countries that implement universal mini-pool nucleic acid testing (MP-NAT) and hepatitis B surface antigen (HBsAg) testing together with confirmatory individual donor nucleic acid testing (ID-NAT) for its blood supply since 2013. The aim of this study was to reappraise the value of HBsAg test in Taiwan's HBV testing strategy.Materials and methods A Markov model was constructed, and cost-effectiveness analysis was conducted in order to reappraise the existing HBV screening strategy in Taiwan. ResultsThe incremental cost-effectiveness ratio (ICER) for the current testing strategy in Taiwan was estimated to be $US 443 154 per quality-adjusted life year (QALY) gained. This is almost six times the willingness-to-pay (WTP) threshold that reflects local preferences.Conclusion Universal HBsAg and MP-8-NAT together with confirmatory ID-NAT testing prevents a significant amount of HBV infections from entering the Taiwan blood supply. However, this comes at a disproportionate increase in cost.

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Section: Introductionmentioning

confidence: 99%