Challenge-based approaches for policy-making in vaccine development and production

Marandi,; Tabatabaeian, SH; Jafari, Parivash; Azarnoosh, M

doi:10.29252/vacres.5.1.7

Cited by 2 publications

(2 citation statements)

References 31 publications

(34 reference statements)

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“…A review of vaccination documents in the Islamic Republic of Iran reveals limited implementation of these innovative approaches in the vaccine development process. To prioritize these issues, it is essential to initiate a political dialogue (Marandi et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Analysis of driving factors influencing vaccine policy in Iran: a cross-impact analysis

Moradi-Lakeh,

Goharinezhad,

Amirkafi

et al. 2024

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Purpose Despite significant progress in Iran's immunization programs, vaccine policymaking in the country still faces various challenges and shortcomings. To address these issues and ensure sustained progress toward achieving comprehensive vaccination policies, it is essential to identify the critical factors influencing vaccine policies in Iran. Our study aims to provide evidence-based insights that can inform the development of effective and equitable vaccine strategies, leading to a more sustainable and efficient approach to vaccination in the country. Design/methodology/approach This mixed-method study aimed to analyze the factors influencing the future of human vaccine policy using Cross Impact Analysis. Firstly, a scoping review was conducted to identify the factors affecting the future of human vaccine development. Secondly, a semi-structured interview was conducted with experts in this field to add more factors and confirm the identified factors within the Iranian context. Finally, a Cross-Impact Analysis (CIA) approach was applied to comprehend the complex relationships between the identified factors. Thematic analysis was used for the qualitative data, and MICMAC analysis was applied to characterize the relationships between the factors. Findings Seventeen key driving force factors were identified through comprehensive review and interviews. These factors were assigned weighted values ranging from zero to three and subsequently analyzed using MICMAC software. Employing the Cross-Impact Analysis (CIA) technique, the study characterized the impact of each factor on vaccine policy and elucidated the intricate interactions between them. The findings underscored that robust leadership and governance, an innovative ecosystem, and well-established immunization information systems emerged as pivotal driving forces shaping vaccine policy in Iran. Research limitations/implications While this study contributes valuable insights into the driving factors influencing vaccine policy in Iran, it is important to acknowledge several limitations. The results rely on the subjective perceptions of a diverse group of specialists, and future research could delve into additional factors in other countries to identify common themes and differences. Practical implications This study provides evidence to assist policymakers in making informed decisions regarding vaccines in Iran. The findings suggest that enhancing access to vaccines, fostering trust in the healthcare system, and prioritizing equity in distribution can contribute to increased vaccination rates and a reduction in vaccine-preventable diseases. Originality/value This study provides a unique contribution to the field of vaccine policy by utilizing the cross-impact analysis to examine the complex interactions among various factors. The results of this analysis demonstrate that these interactions can significantly impact the overall system, highlighting the need for policymakers to consider multiple factors when formulating effective strategies. By revealing the significance of these interactions, this research offers valuable insights into the development of successful policies that can shape a desirable future for vaccine policy in Iran. Future studies could ratify the findings from this research by applying other methodological approaches.

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Section: Introductionmentioning

confidence: 99%

Analysis of driving factors influencing vaccine policy in Iran: a cross-impact analysis

Moradi-Lakeh,

Goharinezhad,

Amirkafi

et al. 2024

View full text Add to dashboard Cite

show abstract

“…A review on the upstream documents in the eld of vaccination in the Islamic Republic of Iran shows the mentioned innovations are seldom implemented in the process of developing vaccines, while in order to prioritize such issues, we rst need to form a political dialogue (14).…”

Section: Introductionmentioning

confidence: 99%

Analysis of Driving Factors Influencing Human Vaccine Development in Iran: a Cross-impact Analysis

Moradi‐Lakeh

Goharinezhad

Amirkafi

et al. 2021

Preprint

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Background: Despite many successes in Immunization programs in Iran, vaccine policymaking has confronted with important weaknesses, and more effort is required to improve progress and prepare for the preferred future. In order to address the challenges facing vaccine development, this study has defined to identify influential factors on the future of development of human vaccines in Iran for strengthening evidence-based policy-making.Method:This mixed-method study aimed to analyze the factors affecting the future of human vaccine development using Cross Impact Analysis. Firstly, with a scoping review, the factors affecting the future of human vaccine development were identified. Secondly, a semi-structured interview was carried out with the determined experts in this sphere to add more factors and confirm the identified factors in the Iran context. Finally, a cross-impact analysis (CIA) approach was applied to understand the complex relationships between the given factors. Thematic analysis was used for the qualitative data and MICMAC analysis was applied for characterizing the relationships between factors.Results: Seventeen key driving forces factors were first identified through reviewing and interviewing. These factors are weighted from zero-three and analyzed by MICMAC software. The CIA technique characterized the effect of each one of these factors on vaccine development and then elaborated on the interaction between them. The results revealed that strong leadership and governance, innovation ecosystem, and immunization information systems were critical driving forces for developing vaccines in Iran. In fact, the degree of influence of these factors is much stronger than the degree of their dependency in the future. So, the vaccine development system is basically dependent on these key drivers. Conclusion: This study explores interactions among factors affecting vaccine development by using cross-impact analysis. It indicates that interactions among the identified factors do have a major influence on the overall system. Understanding the interactions among factors help policymakers formulating successful strategies for shaping a desirable future. Future studies could ratify the findings from this research applying other methodological approaches.

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Challenge-based approaches for policy-making in vaccine development and production

Cited by 2 publications

References 31 publications

Analysis of driving factors influencing vaccine policy in Iran: a cross-impact analysis

Analysis of driving factors influencing vaccine policy in Iran: a cross-impact analysis

Analysis of Driving Factors Influencing Human Vaccine Development in Iran: a Cross-impact Analysis

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