Chalcones and other constituents of Dorstenia prorepens and Dorstenia zenkeri

Abegaz, Berhanu M.; Ngadjui, Bonaventure T.; Dongo, Étienne; Ngameni, Bathélémy; Nindi, Mathew Muzi; Bezabih, Merhatibeb

doi:10.1016/s0031-9422(01)00483-6

Cited by 45 publications

(28 citation statements)

References 15 publications

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“…Moreover, D. brasiliensis may possesses some biologically active compounds similar to other Dorstenia species from the same genus and may thus share similar pharmacological profile. The following compounds and pharmacological activities have been reported in other Dorstenia species: chalcones ( D. prorepens and D. zenkeri ) [96], furocoumarins ( D. bahiensis and D. bryoniifolia ), triterpenes ( D. bahiensis, D. bryoniifolia , D. carauntae, D. cayapiaa, and D. heringerii ) [97]. This is a point to be noted for future research.…”

Section: Discussionmentioning

confidence: 82%

Ethnopharmacology of Medicinal Plants of the Pantanal Region (Mato Grosso, Brazil)

Bieski

Rios-Santos

Oliveira

et al. 2012

Evidence-Based Complementary and Alternative Medicine

138

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Traditional knowledge is an important source of obtaining new phytotherapeutic agents. Ethnobotanical survey of medicinal plants was conducted in Nossa Senhora Aparecida do Chumbo District (NSACD), located in Poconé, Mato Grosso, Brazil using semi-structured questionnaires and interviews. 376 species of medicinal plants belonging to 285 genera and 102 families were cited. Fabaceae (10.2%), Asteraceae (7.82%) and Lamaceae (4.89%) families are of greater importance. Species with the greater relative importance were Himatanthus obovatus (1.87), Hibiscus sabdariffa (1.87), Solidago microglossa (1.80), Strychnos pseudoquina (1.73) and Dorstenia brasiliensis, Scoparia dulcis L., and Luehea divaricata (1.50). The informant consensus factor (ICF) ranged from 0.13 to 0.78 encompassing 18 disease categories,of which 15 had ICF greater than 0.50, with a predominance of disease categories related to injuries, poisoning and certain other consequences of external causes (ICF = 0.78) having 65 species cited while 20 species were cited for mental and behavioral disorders (ICF = 0.77). The results show that knowledge about medicinal plants is evenly distributed among the population of NSACD. This population possesses medicinal plants for most disease categories, with the highest concordance for prenatal, mental/behavioral and respiratory problems.

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Section: Discussionmentioning

confidence: 82%

Ethnopharmacology of Medicinal Plants of the Pantanal Region (Mato Grosso, Brazil)

Bieski

Rios-Santos

Oliveira

et al. 2012

Evidence-Based Complementary and Alternative Medicine

138

View full text Add to dashboard Cite

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“…However, to the best of our knowledge, this is the first report on the isolation of 2 and 3 from Artocarpus species. Compound 2 was previously isolated from Anthyllis hermanniae (Fabaceae) [15], Glycyrrhiza glabra (Leguminosae) [16], and Dorstenia kameruniana (Moraceae) [13], while compound 3 was previously found in Glycyrrhiza glabra [16], Dorstenia mannii [14], as well as D. prorepens and D. zenkeri [17].…”

Section: Resultsmentioning

confidence: 99%

A new prenylated dihydrochalcone from the leaves of Artocarpus lowii

et al. 2008

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A new prenylated dihydrochalcone, 2',4'-dihydroxy-4-methoxy-3'-prenyldihydrochalcone (1), along with two known compounds, 2',4',4-trihydroxy-3'-prenylchalcone (2) and 2',4-dihydroxy-3',4'-(2,2-dimethylchromene)chalcone (3) were isolated from the leaves of Artocarpus lowii. The structures of 1-3 were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compounds 1-3 showed strong free radical scavenging activity towards 2,2-diphenyl-1-picrylhydrazyl (DPPH) measured by electron spin resonance (ESR) spectrometry.

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“…Their occurrence is also particularly relevant in the tribe Heliantheae, and several chalcones have been isolated from Helianthus annuus (Macías et al, 1997). Several chalcones have been also found in the aerial roots of Ficus microcarpa, the roots, stems and leaves of the genus Morus, the leaves and/or fruits of the genus Artocarpus and in members of the genus Dorstenia, all belonging to the family Moraceae (Abegaz et al, 2002;Jayasinghe et al, 2004;Yang et al, 2010). In the family Fabaceae, chalcones are present in Desmodium renifolium, Psoralea corylifolia, roots of the genus Sophora, the genus Glycyrrhiza, and the genus Dalbergia (Bhatt and Dayal, 1992;Friis-Møller et al, 2002;LI et al, 2014).…”

Section: Natural and Synthetic Sources Of Chalconesmentioning

confidence: 99%

Biological Activities and Novel Applications of Chalcones

et al. 2016

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-This review provides information on the biological activities of chalcones (whether natural or synthetic derivatives) on different organisms, as well as an overview of the functions and possible new applications of these plant secondary metabolites on crop protection, as eco-friendly pesticides and weed control agents. Naturally occurring chalcones have been used in traditional medicine for many years; however, recent scientific advances have shown that these molecules have a broad range of biological activities in a variety of organisms. A review on the major sources of chalcones and the main molecular events involved in the modes of action of these natural products is achieved. Chalcones are molecules with a broad spectrum of biological activities, which are of great interest in agriculture to control weeds and unwanted pests.Keywords: mode of action, secondary metabolites, crop protection, pesticide, fungicide, antiviral, phytotoxicity. RESUMO -Esta avaliação fornece informações sobre as atividades biológicas de chalconas (quer derivados naturais ou sintéticos) em diferentes organismos, bem como uma visão geral das funções e eventuais novas aplicações desses metabólitos secundários de plantas em proteção de cultivos e pesticidas orgânicos e para controlar as plantas daninhas. Durante muitos anos têm sido utilizadas na medicina tradicional chalconas de ocorrência natural; no entanto, os recentes avanços científicos têm mostrado que essas moléculas têm vasta gama de atividades biológicas em uma variedade de organismos. Este estudo permite ter uma ideia das principais fontes de chalconas e dos eventos moleculares envolvidos nos principais mecanismos de ação desses produtos naturais. As chalconas são moléculas com um largo espectro de atividade biológica, de grande interesse na agricultura para controlar plantas daninhas e pragas indesejadas.Palavras-chave: modo de ação, metabólitos secundários, proteção de cultivos, pesticida, fungicida, antiviral, fitotoxicidade.

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Chalcones and other constituents of Dorstenia prorepens and Dorstenia zenkeri

Cited by 45 publications

References 15 publications

Ethnopharmacology of Medicinal Plants of the Pantanal Region (Mato Grosso, Brazil)

Ethnopharmacology of Medicinal Plants of the Pantanal Region (Mato Grosso, Brazil)

A new prenylated dihydrochalcone from the leaves of Artocarpus lowii

Biological Activities and Novel Applications of Chalcones

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