Chain-end functionalization of living helical polyisocyanides through a Pd(ii)-mediated Sonogashira coupling reaction

Abstract

End-functionalization is an effective strategy for fabricating functional materials. Installing functional groups onto the chain end of helical polymers is of great interest. In this paper, we reported a new...

Stabilizing Entropically Driven Self-Assembly of Self-Immolative Polyurethanes in Water: A Strategy for Tunable Encapsulation Stability and Controlled Cargo Release

“…To that end, it is desirable they remain stable and show high encapsulation stability, so that premature drug release can be minimized while they are in the blood circulation. Covalent cross-linking of small molecules or polymers has been shown in the literature to achieve high stability of self-assembled nanostructures. ,, However, not much has been explored regarding the stability of noncovalently cross-linked polymeric aggregates. − We thus attempted to evaluate the stability of these supramolecularly cross-linked polymer aggregates by the well-established fluorescence resonance energy transfer (FRET) technique using two lipophilic FRET pairs, namely, 3,3′-dioctadecyloxacarbocyanine perchlorate (DiO) and 1,1′-dioctadecyl-3,3,3′,3′-tetramethyl-indocarbocyanine perchlorate (DiI) as the donor and acceptor chromophore, respectively . The coencapsulation of both of the dyes inside the nanoassemblies will result in effective FRET as donor and acceptor dye molecules will be within their Förster distance inside the core of the micelles (Figure a,b).…”

One-pot asymmetric living copolymerization-induced chiral self-assemblies and circularly polarized luminescence

“…[27][28][29][30][31][32][33][34] Therefore, we recently developed chiral Pd(II)-catalysts bearing bidentate phosphine ligands that initiate an asymmetric living polymerization of achiral diazoacetates to give one-handed PAMs with predictable molar masses (M n ) and low dispersities (M w /M n ). [35][36][37][38] We envisioned that the terminal Pd(II)-complex on the synthesized helical PAMs could be subsequently activated to initiate a block copolymerization of aryl monomers and fabricate p-conjugated block copolymers. The helical PAM block would then drive chiral self-assembly of the generated block copolymers during the polymerization, resulting in polymerization-induced selfassembly (PISA).…”