CHADS2 and CHA2DS2-VASc scores as predictors of left atrial ablation outcomes for paroxysmal atrial fibrillation

Abstract

CHA2DS2-VASc score is an independent predictor of left atrial ablation outcomes for paroxysmal AF, with a similar predictive value to CHADS2. However, the predictive accuracy of both is mediocre.

Comparison of CHADS 2 , R 2 CHADS 2 , and CHA 2 DS 2 -VASc Scores for the Prediction of Rhythm Outcomes After Catheter Ablation of Atrial Fibrillation

“…15 However, there is an emerging role of these scores in the prediction of rhythm outcomes after AF catheter ablation. 7,8,10 First, Saad et al 10 demonstrated that a CHADS 2 score ≥2 was a predictor for LRAF, which was later confirmed by several small studies. 7,18 Recently, Letsas et al 8 showed that both CHADS 2 and CHA 2 DS 2 -VASc scores are associated with rhythm outcomes after catheter ablation.…”

“…7,8,10 First, Saad et al 10 demonstrated that a CHADS 2 score ≥2 was a predictor for LRAF, which was later confirmed by several small studies. 7,18 Recently, Letsas et al 8 showed that both CHADS 2 and CHA 2 DS 2 -VASc scores are associated with rhythm outcomes after catheter ablation. In accordance to previous studies, they demonstrated that a score ≥2 for both CHADS 2 and CHA 2 DS 2 -VASc had the highest predictive value for AF recurrences (AUC, 0.644 and 0.627, respectively).…”

“…2,6 Several studies were performed to identify clinical predictors for AF recurrences after catheter ablation. 7,8 Among those, persistent AF and enlarged left atrial (LA) diameter have reproducibly been shown to associate with AF recurrences, 9 although CHADS 2 and CHA 2 DS 2 -VASc scores were found to be significant predictors in small cohorts. 7,8,10 Similarly, the association between rhythm outcomes and renal dysfunction has been shown recently.…”

“…7,8 Among those, persistent AF and enlarged left atrial (LA) diameter have reproducibly been shown to associate with AF recurrences, 9 although CHADS 2 and CHA 2 DS 2 -VASc scores were found to be significant predictors in small cohorts. 7,8,10 Similarly, the association between rhythm outcomes and renal dysfunction has been shown recently. 11,12 However, the association between rhythm outcomes and the new R 2 CHADS 2 score was not described previously.…”

Catheter Ablation of Lone Atrial Fibrillation

“…Several months later he was subjected to catheter ablation of AF, due to the clinical suspicion of tachyarrhythmia-related cardiomyopathy. obesity, biochemical markers of inflammation, atrial fibrosis on MRI and increased CHADS 2 and CHA 2 DS 2 -VAS C score [18,74,[80][81][82][83][84]. Therefore, among younger patients with lone AF and normal or minimally remodelled LA, not only higher efficiency but also more stable long term effects of catheter ablation can be expected.…”