CFD simulation of transient particle mixing in a high shear mixer

Nguyen, Duy; Rasmuson, Anders; Björn, Ingela Niklasson; Thalberg, Kyrre

doi:10.1016/j.powtec.2014.03.041

Cited by 25 publications

(18 citation statements)

References 19 publications

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“… Predicted mean liquid content and its standard deviation against granule diameter at 450s using (a)

D_{e f f}

=2 × 10 − , test 2 (b)

D_{e f f}

=5 × 10 − , test 1; the error bar indicates the standard deviation of liquid mass fraction at each granule diameter; the target liquid mass fraction in these graphs with a dashed line in case I.…”

Section: Resultsmentioning

confidence: 99%

“…HSG generally has a short processing time and consumes comparatively less liquid binder than fluidized bed or low shear mixer granulators . Furthermore, HSG can handle viscous binders and produce small (<2 mm) granules with high density compared to other granulators, Recent experimental investigations, and numerical investigations,of HSG reveal the advantage of this granulator both at particle scale and granulator scale. The mechanism of granulation (e.g.…”

Section: Introductionmentioning

confidence: 99%

“…Whilst for high shear granulation systems, the discrete element model (DEM) approach can provide predictive capabilities by resolving microscopic particle‐particle and particle‐wall interactions, it suffers from being computationally expensive, making it unattractive to handle realistic situations where a large number of particles are processed . The CFD method (continuum approach) provides an alternative option to simulate the bulk flow in high shear granulation, and recent developments of CFD models and evaluations of its validity on HSG system can be found in the literatures, Darelius et al commented that the advantage of using the Eulerian–Eulerian approach (KTGF+ friction) compared to discrete element methods is that there is no computational limitation on the number of particles being modelled, and thus manufacturing scale granulators can be modelled as well. The CFD model (KTGF + friction) used in the study has been quantitatively validated using experimental data several times.…”

Section: Introductionmentioning

confidence: 99%

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A compartmental CFD‐PBM model of high shear wet granulation

Hounslow

Reynolds

et al. 2016

AIChE Journal

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The conventional, geometrically lumped description of the physical processes inside a high shear granulator is not reliable for process design and scale-up. In this study, a compartmental Population Balance Model (PBM) with spatial dependence is developed and validated in two lab-scale high shear granulation processes using a 1.9L MiPro granulator and 4L DIOSNA granulator. The compartmental structure is built using a heuristic approach based on computational fluid dynamics (CFD) analysis, which includes the overall flow pattern, velocity and solids concentration. The constant volume Monte Carlo approach is implemented to solve the multi-compartment population balance equations. Different spatial dependent mechanisms are included in the compartmental PBM to describe granule growth.It is concluded that for both cases (low and high liquid content), the adjustment of parameters (e.g. layering, coalescence and breakage rate) can provide a quantitative prediction of the granulation process.

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“… Predicted mean liquid content and its standard deviation against granule diameter at 450s using (a)

D_{e f f}

=2 × 10 − , test 2 (b)

D_{e f f}

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A compartmental CFD‐PBM model of high shear wet granulation

Hounslow

Reynolds

et al. 2016

AIChE Journal

Self Cite

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“…The mathematics behind the single models presented have already been well‐publicized. Readers may refer to various research papers and books for further readings, in particular references . In this article, only the key developments are included to in order to help the reader get to grips with the algorithms presented.…”

Section: The Hybrid Modelmentioning

confidence: 99%

Integrating the physics with data analytics for the hybrid modeling of the granulation process

2017

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A hybrid model based on physical and data interpretations to investigate the high shear granulation (HSG) process is proposed. This model integrates three separate component models, namely, a computational fluid dynamics model, a population balance model, and a radial basis function model, through an iterative procedure. The proposed hybrid model is shown to provide the required understanding of the HSG process, and to also accurately predict the properties of the granules. Furthermore, a new fusion model based on integrating fuzzy logic theory and the Dempster‐Shafer theory is also developed. The motivation for such a new modeling framework stems from the fact that integrating predictions from models which are elicited using different paradigms can lead to a more robust and accurate topology. As a result, significant improvements in prediction performance have been achieved by applying the proposed framework when compared to single models. © 2017 American Institute of Chemical Engineers AIChE J, 2017

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“…The half-space adhesion theory has also been extended to elasto-plastic spheres [278] and flat punches [279]. Effective adhesion models are often used to account for adhesion in granular interaction and flow [14,15,280]. Effective adhesion models have also been formulated for capillary adhesion, accounting for the global effect of liquid bridges, e.g., see [12,281,113].…”

Section: Adhesive Contact Of Deformable Spheresmentioning

confidence: 99%

A Survey of Computational Models for Adhesion

Sauer

2015

The Journal of Adhesion

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This work presents a survey of computational methods for adhesive contact focusing on general continuum mechanical models for attractive interactions between solids that are suitable for describing bonding and debonding of arbitrary bodies. The most general approaches are local models that can be applied irrespective of the geometry of the bodies. Two cases can be distinguished: local material models governing the constitutive behavior of adhesives, and local interface models governing adhesion and cohesion at interfaces in the form of traction-separation laws. For both models various subcategories are identified and described, and used to organize the available literature that has contributed to their advancement. Due to their popularity and importance, this survey also gives an overview of effective adhesion models that have been formulated to characterize the global behavior of specific adhesion problems.

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CFD simulation of transient particle mixing in a high shear mixer

Cited by 25 publications

References 19 publications

A compartmental CFD‐PBM model of high shear wet granulation

A compartmental CFD‐PBM model of high shear wet granulation

Integrating the physics with data analytics for the hybrid modeling of the granulation process

A Survey of Computational Models for Adhesion

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