“…As a consequence, the simulation of an entire experimental channel 15.4 cm long and wide would require an excessive number of computational cells and prohibitive simulation times. In order to sort this issue out, it is very common in the literature to adopt the Unit Cell approach [26,31,32,48,49]. Apart from the regions next to the inlet, the outlet or the lateral boundaries of the channel, the flow field is periodic so that only a very small domain (Unit Cell, containing one or more spacer meshes) is simulated as representative of the whole channel.…”