CFD-Based Postprocessing of CT-MRI Data to Determine the Mechanics of Rupture in Abdominal Aortic Aneurysms

Canchi, Tejas; Ng, E. Y. K.; Saxena, Ashish; Narayanan, Sriram

doi:10.1007/978-3-319-98974-7_4

Cited by 6 publications

(6 citation statements)

References 40 publications

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“…Deriving the geometry features from the CTA and blood flow parameters from MRI [91], a patient-specific carotid hemodynamic can be studied using computational fluid dynamics (CFD) [92]. In the past, it is shown that CFD-based flow analysis can facilitate an accurate and early prediction of the plaque prone to rupture [93].…”

Section: Introductionmentioning

confidence: 99%

Imaging modalities to diagnose carotid artery stenosis: progress and prospect

2019

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In the past few decades, imaging has been developed to a high level of sophistication. Improvements from one-dimension (1D) to 2D images, and from 2D images to 3D models, have revolutionized the field of imaging. This not only helps in diagnosing various critical and fatal diseases in the early stages but also contributes to making informed clinical decisions on the follow-up treatment profile. Carotid artery stenosis (CAS) may potentially cause debilitating stroke, and its accurate early detection is therefore important. In this paper, the technical development of various CAS diagnosis imaging modalities and its impact on the clinical efficacy is thoroughly reviewed. These imaging modalities include duplex ultrasound (DUS), computed tomography angiography (CTA) and magnetic resonance angiography (MRA). For each of the imaging modalities considered, imaging methodology (principle), critical imaging parameters, and the extent of imaging the vulnerable plaque are discussed. DUS is usually the initial recommended CAS diagnostic examination. However, for the therapeutic intervention, either MRA or CTA is recommended for confirmation, and for added information on intracranial cerebral circulation and aortic arch condition for procedural planning. Over the past few decades, the focus of CAS diagnosis has also shifted from pure stenosis quantification to plaque characterization. This has led to further advancement in the existing imaging tools and development of other potential imaging tools like Optical coherence tomography (OCT), photoacoustic tomography (PAT), and infrared (IR) thermography.

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Section: Introductionmentioning

confidence: 99%

Imaging modalities to diagnose carotid artery stenosis: progress and prospect

2019

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“…The effect of compliance wall model was analysed for predicting various parameters (Bazilevs et al, 2006; Berguer et al, 2006; Menter et al, 2004; Sun et al, 2015; Tan et al, 2009; Torii, Wood, et al, 2009; Vallez et al, 2015). Various CFD analysis have been performed with different parameters and various numerical model assumptions such as, blood as Newtonian or non‐Newtonian fluid, flow as laminar or turbulent, pulsatile or constant flow (Benim et al, 2011; Febina et al, 2018; Gharahi et al, 2016; Metaxa et al, 2010; Stevens et al, 2017), different viscosity model (Canchi et al, 2018) and so forth. Based on the literatures the solving with blood as Non‐Newtonian fluid with a pulsatile flow under laminar flow condition predicts a reasonable WSS and the same has been used in the current study.…”

Section: Introductionmentioning

confidence: 99%

“…Metaxa et al (2010) has studied the effect of WSS in growth of aneurysm in a Rabbit model. Canchi et al (2018) has studied the rupture risk assessment in abdominal aortic aneurysm using multimodal imaging and CFD. Very limited literature is available to understand the effect of WSS in CA aneurysm in bifurcation region (rigid and compliant vessel) including dynamic growth of aneurysm in rest and exercise conditions and if such analysis is carried out it would be a good addition in systematic approach for pre‐planning of necessary clinical interventions.…”

Section: Introductionmentioning

confidence: 99%

Numerical investigation of hemodynamic pattern in carotid artery dynamic aneurysm on bifurcation region for early clinical decision making

Sikkandar

Almedhun

2022

Expert Systems

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In this paper, a numerical estimation of wall shear stress (WSS) and study on hemodynamic pattern in carotid artery (CA) near the bifurcation region with dynamic growth of aneurysm using computational fluid dynamics (CFD) for making early clinical decision is presented. Aneurysm in the carotid artery affects the blood supply to brain and if it is untreated at early stage may lead to sudden death. Computed tomography images of four different cases of stroke subjects scanned of 600 slices with 1 mm resolution with neighbouring layers from neck to head are considered for this study. Numerically a CA with bifurcation region is developed from these images and aneurysm is and allowed to grow dynamically from 10 to 20 mm. WSS and hemodynamic pattern is estimated numerically using Ansys platform at various region of interest in both rigid and compliant wall conditions. The arterial wall thinning was analytically estimated using thick cylinder theory to estimate the increase in aneurysm under various stress conditions (rest and exercise conditions). The findings show that WSS is found to reduce at the aneurysm region with a corresponding strong vortex pattern. Thus, the vortex pattern could be the cause of tissue damage and thinning rather than WSS. The corresponding increase in velocity gradient at the bifurcation region is also captured. This high gradient is the cause for higher WSS at the bifurcation region which is a possible cause for the formation of plaque and arteriosclerosis. It is interesting to note that the WSS did not change drastically for 10 and 15 mm aneurysm but a large change was seen from normal to 10 and 15–20 mm respectively. This study provides a better clinical insight on the effect of aneurysm in CA bifurcation region using a systematic approach to numerical modelling compared to traditional imaging modalities. It can be used as an adjunct tool for physicians and surgeons for planning necessary clinical interventions.

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“…Deriving the geometry features from the CTA and blood flow parameters from MRI [123], a patient-specific carotid hemodynamic can be studied using computational fluid dynamics (CFD) [124]. In the past, it is shown that CFD-based flow analysis can facilitate an accurate and early prediction of the plaque prone to rupture [125].…”

Section: Current Trends and Prospectsmentioning

confidence: 99%

“…are used [123,128]. However, given the need of intravenous contrast agent and the cost of the examination [20], [21], the patient-specific data is not readily available.…”

Section: Introductionmentioning

confidence: 99%

Carotid artery stenosis (CAS) disease detection by passive and active medical infrared (IR) thermal imaging

Saxena¹

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CFD-Based Postprocessing of CT-MRI Data to Determine the Mechanics of Rupture in Abdominal Aortic Aneurysms

Cited by 6 publications

References 40 publications

Imaging modalities to diagnose carotid artery stenosis: progress and prospect

Imaging modalities to diagnose carotid artery stenosis: progress and prospect

Numerical investigation of hemodynamic pattern in carotid artery dynamic aneurysm on bifurcation region for early clinical decision making

Carotid artery stenosis (CAS) disease detection by passive and active medical infrared (IR) thermal imaging

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