Cessation Outcomes Among Treatment-Seeking Menthol and Nonmenthol Smokers

D’Silva, Joanne; Boyle, Raymond G.; Lien, Rebecca K.; Rode, Peter; Okuyemi, Kolawole S.

doi:10.1016/j.amepre.2012.07.033

Cited by 34 publications

(30 citation statements)

References 16 publications

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“…Prevalence estimates among men ranged from 8.2% to 30.5%, while estimates among women ranged from 22.7% to 69.5%, depending on study sample and year of publication. The highest prevalence among women was found in a study of Minnesota Quitline callers from 2009–2011 (13). We did not identify any estimates published since 2011 of gender differences in the prevalence of menthol use among Black smokers.…”

Section: Resultsmentioning

confidence: 99%

Gender and Menthol Cigarette Use in the USA: A Systematic Review of the Recent Literature (2011–May 2017)

et al. 2017

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Purpose of review To summarize current research on gender differences in mentholated cigarette use and related outcomes. Secondarily, to summarize literature on gender differences in mentholated cigarette use and related outcomes among Black smokers. Recent findings Women smokers are more likely to use menthol cigarettes than men. Other than prevalence, there is a paucity of research on gender differences in menthol related outcomes (e.g., cessation, disease). Among both women and men, menthol preference is stable during adolescence and young adulthood. A substantial portion of both women and men who smoke menthol report an expectation of quitting should menthol be banned. We did not identify any studies of gender differences in mentholated cigarette use among Black smokers. Summary Despite public health relevance, there is little current research on gender differences in mentholated cigarette use, other than studies of prevalence, and very little research on gender differences among Black smokers, including prevalence.

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Section: Resultsmentioning

confidence: 99%

Gender and Menthol Cigarette Use in the USA: A Systematic Review of the Recent Literature (2011–May 2017)

et al. 2017

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“…A review of studies with long-term cessation outcomes (6 months to >5 years) also supports the conclusion that menthol does not increase dependence. Many studies have reported that there is no difference in cessation and no effect of menthol on various long-term cessation outcomes overall 28,61,66,68,80,81,85,96,104,115,119–123 or in specific subgroups, such as among White and Hispanic smokers 58 and among those who received placebo gum or motivational interview. 68 Fu et al 35 reported that menthol smokers who received an intervention had increased odds of cessation as compared to nonmenthol smokers.…”

Section: Discussionmentioning

confidence: 99%

“…These studies generally report findings that are mixed, with some results suggesting shorter TTFC, some longer TTFC, and some with no difference in TTFC for menthol versus nonmenthol smokers. 62,96,97 …”

Section: Literature Reviewmentioning

confidence: 99%

Predictors, Indicators, and Validated Measures of Dependence in Menthol Smokers

Frost-Pineda

Muhammad-Kah

Rimmer

et al. 2014

Journal of Addictive Diseases

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This article presents a comprehensive review of the menthol cigarette dependence-related literature and results from an original analysis of the Total Exposure Study (TES), which included 1,100 menthol and 2,400 nonmenthol adult smokers. The substantial scientific evidence available related to age of first cigarette, age of regular use, single-item dependence indicators (smoking frequency, cigarettes per day, time to first cigarette, night waking to smoke), smoking duration, numerous validated and widely accepted measures of nicotine/cigarette dependence, and our analysis of the TES do not support that menthol smokers are more dependent than nonmenthol smokers or that menthol increases dependence.

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“…Recent reports, including a report by the Food and Drug Administration Tobacco Products Scientific Advisory Committee, have concluded that menthol cigarettes promote the initiation of smoking behavior, facilitate the progression to regular smoking, and weaken the motivation to quit smoking in established smokers (Anderson 2011a; b; Benowitz and Samet 2011; TPSAC 2011). Compared with nonmenthol cigarette smokers, young menthol cigarette smokers are prone to nicotine dependence, demonstrated by several measurements of nicotine dependence, such as time to first cigarette, smoking craving, and quit rates (Collins and Moolchan 2006; D’Silva et al 2012; Hersey et al 2006; Hersey et al 2010; Levy et al 2011; Nonnemaker et al 2013; Smith et al 2014; Wackowski and Delnevo 2007). Similarly, adult smokers who use menthol cigarettes presented heightened nicotine addiction and were more likely to smoke their first cigarette sooner after waking and inhale more deeply (Ahijevych and Parsley 1999; Fagan et al 2010; Hoffman and Simmons 2011; Hymowitz et al 1995; Muscat et al 2009; Okuyemi et al 2003; Richter et al 2008), leading to elevated levels of both serum nicotine and exhaled carbon monoxide (Williams et al 2007).…”

Section: Introductionmentioning

confidence: 99%

Enhancing effect of menthol on nicotine self-administration in rats

et al. 2016

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Rationale Tobacco smoking is a leading preventable cause of premature death in the United States. Menthol is a significant flavoring additive in tobacco products. Clinical evidence suggests that menthol may promote tobacco smoking and nicotine dependence. However, it is unclear whether menthol enhances the reinforcing actions of nicotine and thus facilitates nicotine consumption. This study employed a rat model of nicotine self-administration to examine the effects of menthol on nicotine-taking behavior. Methods Male Sprague-Dawley rats were trained in daily 1-h sessions to press a lever for intravenous nicotine self-administration under a fixed-ratio 5 schedule of reinforcement. In separate groups, rats self-administered nicotine at four different doses (0.0075, 0.015, 0.03, and 0.06 mg/kg/infusion). Five minutes prior to the two test sessions, menthol (5 mg/kg) or its vehicle was administered intraperitoneally in all rats in a counterbalanced design within each group. In separate rats that self-administered 0.015 mg/kg/infusion nicotine, menthol dose-response function was determined. Menthol was also tested on food self-administration. Results An inverted U-shaped nicotine dose-response curve was observed. Menthol pretreatment shifted the nicotine dose-response curve to the left. The facilitating effect of menthol on the self-administration of 0.015 mg/kg/infusion nicotine was dose-dependent, whereas it produced similar effects at doses above the threshold of 2.5 mg/kg. Menthol tended to suppress the self-administration of food pellets. Conclusions These data demonstrate that menthol enhances the reinforcing effects of nicotine, and the effect of menthol was specific to nicotine. The findings suggest that menthol directly facilitates nicotine consumption, thereby contributing to tobacco smoking.

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Cessation Outcomes Among Treatment-Seeking Menthol and Nonmenthol Smokers

Cited by 34 publications

References 16 publications

Gender and Menthol Cigarette Use in the USA: A Systematic Review of the Recent Literature (2011–May 2017)

Gender and Menthol Cigarette Use in the USA: A Systematic Review of the Recent Literature (2011–May 2017)

Predictors, Indicators, and Validated Measures of Dependence in Menthol Smokers

Enhancing effect of menthol on nicotine self-administration in rats

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