Cesarean Scar Pregnancy: Comparing the Efficacy and Tolerability of Treatment with High-Intensity Focused Ultrasound and Uterine Artery Embolization

Xiao, Jianghong; Shi, Zongjie; Zhou, Jinshui; Ye, Jun; Zhu, Jinmin; Zhou, Xin; Wang, Fang; Zhang, Shouhua

doi:10.1016/j.ultrasmedbio.2016.11.001

Cited by 28 publications

(33 citation statements)

References 26 publications

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“…No additional treatment was necessary. During follow-up, serum b-hCGof all the patients in the three groups returned to normal levels in $30 days, which was similar to previous reports [13,14,19]. Although uterine perforation at a previous caesarean scar during D&C procedure has been reported in other studies [14], this complication didn't occur in our study.…”

Section: Discussionsupporting

confidence: 91%

“…A study in 2017 hypothesized that having a menolipsis time longer than 51 days and a gestational sac larger than 27 mm were risk factors for CSP patients with intraoperative hemorrhage [18]. Furthermore, in another study there was no serious adverse effects found, including heavy hemorrhaging, in which the HIFU treatment group had a small average gestational sac/mass diameter of 25.03 ± 8.75 mm [19].…”

Section: Discussionmentioning

confidence: 99%

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The impact of gestational sac size on the effectiveness and safety of high intensity focused ultrasound combined with ultrasound-guided suction curettage treatment for caesarean scar pregnancy

Zhang

et al. 2018

International Journal of Hyperthermia

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

The impact of gestational sac size on the effectiveness and safety of high intensity focused ultrasound combined with ultrasound-guided suction curettage treatment for caesarean scar pregnancy

Zhang

et al. 2018

International Journal of Hyperthermia

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“…The failure of treatment was defined as complications such as vaginal bleeding of more than 200 ml, a decrease in the serum β-hCG level by ≤50% for the seventh day, or treated by second line therapy such as Foley balloon catheter insertion, laparoscopy, or laparotomy (Xiao et al, 2017).…”

Section: Treatment Assessment and Follow-upmentioning

confidence: 99%

Clinical Assessment of Ultrasound-Guided Local Lauromacrogol Injection Combined With Curettage and Hysteroscopy for Cesarean Scar Pregnancy

Liu

Zhu

et al. 2020

Front. Pharmacol.

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Background: To evaluate the efficacy, safeness and cost of ultrasound-guided local lauromacrogol injection (USG-LLI) combined with curettage and hysteroscopy for cesarean scar pregnancy (CSP).Methods: This was a retrospective study included 151 CSP patients diagnosed with CSP from June 2017 to December 2019, and treated by USG-LLI (n = 86) or uterine artery embolization (UAE) (n = 65) combined with curettage and hysteroscopy. Clinical data and outcome were analyzed.Results: There were no significant differences in basic clinical characteristics in the two groups. Two groups showed the similar success rates. USG-LLI group, compared with UAE group had significantly lower complication rates (9.30 vs. 44.62%), lower total costs (both medical and non-medication cost) (p < 0.05).Conclusions: USG-LLI combined with curettage and hysteroscopy is a feasible method to treat CSP with minimal invasion and high efficacy. Moreover, compared with curettage after UAE, USG-LLI exhibited lower complication rate and required fewer expenses.

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“…The main application areas of HIFU are the treatment of soft tissue tumors [5], [6] in liver [7], kidney [8], prostate [9], [10], breast [11], and in the brain [12], [13]. HIFU is not limited to the treatment of soft tissue tumors, and exploration of new avenues such as triggered drug delivery [14], treatment of bone tumors [15], neurological disorders [16], ectopic implantation [17], and pain management [18], [19] continues.…”

Section: Introductionmentioning

confidence: 99%

HIFU Drive System Miniaturization Using Harmonic Reduced Pulsewidth Modulation

Adams

Carpenter

Cowell

et al. 2018

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

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Switched excitation has the potential to improve on the cost, efficiency, and size of the linear amplifier circuitry currently used in high-intensity focused ultrasound (HIFU) systems. Existing switching schemes are impaired by high harmonic distortion or lack array apodisation capability, so require adjustable supplies and/or large power filters to be useful. A multilevel pulsewidth modulation (PWM) topology could address both of these issues but the switching-speed limitations of transistors mean that there are a limited number of pulses available in each waveform cycle. In this study, harmonic reduction PWM (HRPWM) is proposed as an algorithmic solution to the design of switched waveforms. Its appropriateness for HIFU was assessed by design of a high power five-level unfiltered amplifier and subsequent thermal-only lesioning of ex vivo chicken breast. Three switched waveforms of different electrical powers (16, 26, 35 W) were generated using the HRPWM algorithm. Lesion sizes were measured and compared with those made at the same electrical power using a linear amplifier and bi-level excitation. HRPWM produced symmetric, thermal-only lesions that were the same size as their linear amplifier equivalents (\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{upgreek} \usepackage{mathrsfs} \setlength{\oddsidemargin}{-69pt} \begin{document} }{}$p > 0.05$ \end{document}). At 16 W, bi-level excitation produced smaller lesions but at higher power levels large transients in the acoustic waveform nucleated undesired cavitation. These results demonstrate that HRPWM can minimize HIFU drive circuity size without the need for filters to remove harmonics or adjustable power supplies to achieve array apodisation.

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Cesarean Scar Pregnancy: Comparing the Efficacy and Tolerability of Treatment with High-Intensity Focused Ultrasound and Uterine Artery Embolization

Cited by 28 publications

References 26 publications

The impact of gestational sac size on the effectiveness and safety of high intensity focused ultrasound combined with ultrasound-guided suction curettage treatment for caesarean scar pregnancy

The impact of gestational sac size on the effectiveness and safety of high intensity focused ultrasound combined with ultrasound-guided suction curettage treatment for caesarean scar pregnancy

Clinical Assessment of Ultrasound-Guided Local Lauromacrogol Injection Combined With Curettage and Hysteroscopy for Cesarean Scar Pregnancy

HIFU Drive System Miniaturization Using Harmonic Reduced Pulsewidth Modulation

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