Cervicofacial cellulitis: The impact of non-steroidal anti-inflammatory drugs. A study of 70 cases

Bennani-Baïti, A.A.; Benbouzid, A.; Essakalli-Hossyni, L.

doi:10.1016/j.anorl.2015.06.004

Cited by 19 publications

(24 citation statements)

References 20 publications

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“…Because this mechanism of action is distinct from that of opioids, NSAIDs have the potential to produce adequate levels of pain relief while reducing overall opioid requirements and associated AEs [ 17 ]. However, NSAIDs are associated with their own potential AEs, including gastropathy, renal impairment, potential to prolong bleeding via platelet inhibition [ 16 ], and possible increased risk of severe infection [ 18 ] or acceleration of an infectious disease course [ 19 ]. As such, it is important to characterize the evidence for benefits and risks associated with NSAID use in order to determine their clinical utility as part of the pain management strategy for pediatric patients.…”

Section: Introductionmentioning

confidence: 99%

Pain Management in Children: NSAID Use in the Perioperative and Emergency Department Settings

Cooney

2021

Pediatr Drugs

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Nonsteroidal anti-inflammatory drugs (NSAIDs) are often used for pediatric pain management in the emergency setting and postoperatively. This narrative literature review evaluates pain relief, opioid requirements, and adverse effects associated with NSAID use. A PubMed search was conducted to identify randomized controlled trials evaluating the use of conventional systemic NSAIDs as pain management for children in the perioperative or emergency department (traumatic injury) setting. Trials of cyclooxygenase-2 inhibitors ("coxibs") were excluded. Search results included studies of ibuprofen (n = 12), ketoprofen (n = 5), ketorolac (n = 6), and diclofenac (n = 4). NSAIDs reduced the opioid requirement in 10 of 13 studies in which this outcome was measured. NSAID use did not compromise pain relief; NSAIDs provided improved or similar pain scores compared with opioids (or other control) in 24 of 27 studies. Adverse event frequencies were reported in 26 studies; adverse event frequencies with NSAIDs were lower than with opioids (or other control) in three of 26 studies, similar in 21 of 26 studies, and more frequent in two of 26 studies. Perioperative and emergency department use of NSAIDs may reduce opioid requirements while maintaining pain control, with similar or reduced frequencies of opioid-associated adverse events.

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Section: Introductionmentioning

confidence: 99%

Pain Management in Children: NSAID Use in the Perioperative and Emergency Department Settings

Cooney

2021

Pediatr Drugs

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“…From an epidemiological point of view, the 2007 study by Rakotoarison et al [10] showed an increase in the number of cases of cervicofacial cellulitis due to the misuse of drugs, especially in cases of self-medication with uncontrolled antiinflammatory drugs and antibiotics. Nonsteroidal anti-inflammatory drug abuse is found in more than half of the cases (up to 80%) according to the study by Bennani-Baïta et al [11]. Among the subjects most affected by diffuse cellulitis are men aged between 20 and 30 years, patients with poor oral hygiene, and those belonging to poor socioeconomic classes.…”

Section: Discussionmentioning

confidence: 99%

“…Local homecare for tracheostomy opening and cervicotomy scar was provided by a nurse, and regular clinical checks in the maxillofacial surgery department were performed, with a favorable prognosis. Consultation with a dental surgeon was necessary for general prosthetic rehabilitation with the extraction of the remaining non-conservable teeth (11,12, and 23) and making of complete maxillary and mandibular removable prostheses.…”

Section: Casementioning

confidence: 99%

Gangrenous cervicofacial cellulitis from odontogenic infection: two clinical cases

Hoarau

Folia

Zwetyenga

et al. 2019

J Oral Med Oral Surg

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Introduction: Cervicofacial cellulitis resulting from common odontogenic infections is rare but serious, with life-threatening complications and potential general or local complications. Observation: Two cases are discussed here. The first observed case concerned a 32-year-old patient, affected by gangrenous cellulitis, following the avulsion of teeth number 38. The second observed case was of a chronic periapical infection being left untreated. The urgency of these two cases required the coordination of medical and surgical specialist teams to ensure a stable and successful treatment, involving surgical treatment, drug therapy, and reanimation. Discussion: The inadequate treatment or chronic dental infections, associated with immunosuppression and some cofactors (tobacco, alcohol, drugs, pregnancy, etc.), can lead to severe case of cellulitis. Medical and surgical management should be carried out as soon as possible to prevent the onset of serious complications such as mediastinitis, septic shock, and thrombophlebitis.

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“…If the infection is of sinus origin, this group is the most frequently found (18%), followed by staphylococci (17%) and Gram-negative bacteria (15%). Taking NSAIDs is a likely risk factor, or at least an aggravating factor, even though no studies could scientifically prove it [6]. NSAIDs alleviate symptoms and delay diagnosis.…”

Section: Discussionmentioning

confidence: 99%

From dental infection to extradural empyema: a case report

Comte

Hasnaoui

2019

J Oral Med Oral Surg

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Introduction: Brain infections of dental origin are rare, but well-known and accurately described. There are two different brain infections: brain abscess, the most frequent, and extradural or subdural empyema. Here, we discuss the case of an extradural empyema. Observation: A 28-year-old man with a very poor dental condition showed neurological and eye infection signs. A brain and face CT scan revealed extradural empyema, orbit abscess and pansinusitis. These infections had all dental origin: an apical lesion of tooth 26. Discussion: Such severe cases must be surgically and medically treated with a strong antibiotic therapy. A systematic investigation and the treatment of dental infected areas are both necessary.

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Cervicofacial cellulitis: The impact of non-steroidal anti-inflammatory drugs. A study of 70 cases

Cited by 19 publications

References 20 publications

Pain Management in Children: NSAID Use in the Perioperative and Emergency Department Settings

Pain Management in Children: NSAID Use in the Perioperative and Emergency Department Settings

Gangrenous cervicofacial cellulitis from odontogenic infection: two clinical cases

From dental infection to extradural empyema: a case report

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