Cervical spondylodiscitis as a rare presentation of neck pain in a systemically well patient

Abstract

DESCRIPTIONWe present a case of a 73-year-old woman with gradual onset severe neck pain for 5 days, radiating to head and shoulders. Her medical history included osteoarthritis and cervical spondylosis. On examination she was non-feverish, systemically well with no neurological signs. Movements were limited by pain and no focal spinal tenderness was found. A C reactive protein of 263 and erythrocyte sedimentation rate of 83 in the absence of a clear alternative infective source prompted further investigation.MRI of the cervical spine in the short T1 inversion recovery sequence demonstrated a subtle increase in signal in the C5-C6 disc with prevertebral and postvertebral oedema (figure 1). The T1 sequence is highly suspicious of an early discitis, with disruption of the usually smooth end plate of C5 (figure 2). A repeat MRI with gadolinium highlights more clearly the high signal in the anterior disc and surrounding soft tissues (figure 3).Spondylodiscitis can have serious consequences from local destruction, neurological involvement or as a source of sepsis. Patients can present with nonspecific pain only with fever in as few as 14% of cases, 1 and positive blood culture in as few as 39%.2 MRI with gadolinium enhancement significantly improves sensitivity enhancing the disc, vertebral surfaces and surrounding soft tissue giving better distinction between degenerative changes and infective lesions.3 There are numerous treatment regimens but in the absence of positive cultures empirical intravenous antibiotics targeting Staphylococcus aureus were used. A 2-week course of flucloxacillin with teicoplanin for 4 weeks as an outpatient showed resolution both clinically and biochemically. There is enhancement (high signal) within the C5/6 disc anteriorly and within the adjacent C5 and C6 vertebrae. There is also enhancement within the thickened prevertebral soft tissues and within the soft tissues adjacent to the cervical posterior elements.

Factors related to post surgical neurologic improvement for cervical spine infection

“…Clinicians should be alert to the possibility of cervical disease when patients present with neck pain and neurological deficits; uncharacteristic symptoms may delay the use of conventional radiography [2] , [16] , [17] , [18] , and thereby delay the final diagnosis by 12–15 weeks [5] , [6] . The neck pain related to cervical spine infection is basically a posterior nuchal, gradual onset, aggravating and intractable pain, sometimes associated with resting and night pain, and cannot be relieved by specific neck movement [19] . The neck pain is often reported to be the leading symptom of cervical spine infection.…”