Cervical spine involvement in patients with chronic arthritis undergoing orthopaedic surgery.

Ornilla, Enrique; Ansell, Barbara M.; Swannell, A J

doi:10.1136/ard.31.5.364

Cited by 27 publications

(4 citation statements)

References 8 publications

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“…Moreover MRI reduces radiation exposure, which is especially important in young children. Clearly not all JIA patients need an MR examination of the cervical spine: patients with persistent oligoarthritis do not, or only rarely, develop cervical spine disease [ 3 , 11 , 28 - 33 ], however in polyarticular disease cervical spine involvement is frequent both in rheumatoid factor positive and negative patients [ 9 , 11 ]. Hence we would recommend MR imaging in the following situations: (1) signs and symptoms of cervical spine involvement, (2) rheumatoid factor positive and (3) rheumatoid factor negative polyarthritis or extended oligoarthritis with recalcitrant disease necessitating intensive therapy.…”

Section: Discussionmentioning

confidence: 99%

Cervical spine involvement in patients with juvenile idiopathic arthritis - MRI follow-up study

et al. 2014

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BackgroundTo describe MRI and clinical findings in patients with juvenile idiopathic arthritis with cervical spine involvement at onset and follow-up under therapy.Methods13 patients with signs of cervical spine involvement in juvenile idiopathic arthritis with a median disease duration of 1.7 years were included in the study. Clinical records and MR images were retrospectively analyzed according to symptoms and findings concerning the cervical spine.ResultsAt the onset of cervical spine involvement all patients showed limited range of motion, whereas only 5 of them complained of pain. In MR images joint hyperintensity, contrast enhancement, malalignment, ankylosis, erosion and narrowing of the spinal canal at cranio-cervical junction were found at 28, 32, 15, 2, 2 and 3 sites in 12 (93%), 13 (100%), 8 (62%), 2 (15%), 2 and 3 (20%) patients respectively. 3 of the 5 patients with pain (60%) showed ankylosis, erosions or narrowing of the spinal canal at cranio-cervical junction on MRI. At follow-up - after a median disease duration of cervical spine arthritis of 2.1 years and a variable duration of treatment with methotrexate (all patients) and biological agents (12 patients) - joint hyperintensity, enhancement and malalignment decreased to 15, 19 and 6 sites in 10 (77%), 11 (85%) and 3 (20%) patients respectively whereas ankylosis, erosion and narrowing of the spinal canal at cranio-cervical junction increased to 7, 6 and 4 sites in 3 (20%), 4 (31%) and 4 patients respectively. Pain was no longer reported, but 9 of 13 (69%) patients still had a limited range of motion with 6 of them (46%) showing skeletal changes on MRI.ConclusionsThis first MRI based follow-up study shows that cervical spine arthritis can follow a severe disease course in juvenile arthritis. While malalignments and inflammation sites decreased osseous changes with erosions, ankylosis, and narrowing of the spinal canal increased under treatment despite only minor subjective complaints. Therefore close MRI monitoring of these patients appears to be reasonable.

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Section: Discussionmentioning

confidence: 99%

Cervical spine involvement in patients with juvenile idiopathic arthritis - MRI follow-up study

et al. 2014

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“…The condition is associated with a long duration of rheumatoid disease and multifocal severe affections of the joints (Ornilla et al 1972 Weissman et al 1982).…”

Section: Discussion 'mentioning

confidence: 99%

Posterior atlanto-axial subluxation in rheumatoid arthritis

Santavirta

Sandelin

Slätis

1985

Acta Orthopaedica Scandinavica

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“…They may have also myalgias and tenosynovitis and arthritis which may be oligoarticular to polyarticular. (3) The widely affected joints include wrists, knee, and ankles; but any joint can be affected, even the temporomandibular joints(5), cervical spine (6), hips (7), and the small joints of the hand and feet. SoJIA may present as painless lymphadenopathy (25%) hepatomegaly, splenomegaly or pericarditis which may be complicated by cardiac tamponade (3,4) There is no specific laboratory features that distinguishes SoJIA from other conditions, but the pattern of laboratory abnormalities may support the diagnosis, for examples; microcytic hypochromic anaemia, neutrophilic leucocytosis, thrombocytosis, high ESR, high CRP, high serum ferritin, low serum albumin, mildly elevated AST, high D-dimer and negative autoantibodies.…”

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confidence: 99%

Systemic-Onset Juvenile Idiopathic Arthritis with unusual Cutaneous Manifestation and peripheral eosinophilia: Case Report

Alameen

Elamin

2023

Preprint

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Cervical spine involvement in patients with chronic arthritis undergoing orthopaedic surgery.

Cited by 27 publications

References 8 publications

Cervical spine involvement in patients with juvenile idiopathic arthritis - MRI follow-up study

Cervical spine involvement in patients with juvenile idiopathic arthritis - MRI follow-up study

Posterior atlanto-axial subluxation in rheumatoid arthritis

Systemic-Onset Juvenile Idiopathic Arthritis with unusual Cutaneous Manifestation and peripheral eosinophilia: Case Report

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