“…The most frequent etiologies of spinal dysraphism include low socioeconomic level, inadequate folic acid intake, diabetes mellitus, obesity, vitamin B 12 deficiency, high body temperature, valproic acid, metabolic teratogenic agents, and environmental contamination. In their series of seven patients, mothers of all seven had not taken folic acid supplementation during their pregnancy,[ 6 ] although 2/10 patients gave similar history in our series.…”