Cervical Lymphadenopathy in Childhood Epidemiology and Management

Papadopouli, Evangelia; Michailidi, Eleni; Papadopoulou, Eleftheria; Paspalaki, P.; Vlahakis, Ioannis; Kalmanti, Maria

doi:10.1080/08880010903091848

Cited by 8 publications

(9 citation statements)

References 9 publications

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“…This present study has got similar result where 89.13% of all malignant cervical lymphadenopathy were squamous cell carcinoma followed by adenocarcinoma. These findings are similar to studies conducted by Chhotray and Acharya, Frable WJ, Pilloti et al 7,8,9 Kline et al found that specific primary site identification was accurate with proper clinical history, examination and investigation. But they also mentioned that with occult primary tumour, errors in specific primary site designation were more frequent.…”

Section: Discussionsupporting

confidence: 89%

Pattern of Head and Neck Malignancies in North Eastern India - A Hospital Based Prospective Study

Chowdhury¹

2019

jebmh

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BACKGROUND Head and neck malignancy is one of the common cancers worldwide with an increasing number in the subcontinent. Oral cavity is by far the most predominant location in the head and neck region for primary malignant tumours. Metastases to head and neck area can occur either from local structures or from distant organs. In most cases, the head and neck region is the primary site for metastasis. In North Eastern part of India, the prevalence was found to be as high as 54.48%. Such high prevalence in this region is indicative of several factors that predispose to HNCA. METHODS 100 patients with suspected head and neck neoplasm where malignancy was proved by biopsy were included in this study. A detailed history of their socio-cultural background like community, religion, food habit, substance abuse, age, sex, occupation etc. was taken and analysed. RESULTS The overall frequency of malignancy was higher in males (70.6%) with male: female ratio 2.4: 1 with highest incidence in 5th to 6 th decade. Metastatic neck node was found in 74.13% of patients with occult primary in 1.72% of them. Histologically 74.86% were squamous cell carcinomas. Primary site was predominantly hypopharynx with 39.02% incidence. CONCLUSIONS Head and neck malignancies are more common in elderly males in their 5 th and 6 th decade and majority of these are squamous cell carcinomas which presented as metastatic neck nodes.

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Section: Discussionsupporting

confidence: 89%

Pattern of Head and Neck Malignancies in North Eastern India - A Hospital Based Prospective Study

Chowdhury¹

2019

jebmh

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“…Lymphadenopathy due to tuberculosis was found in (78.6%) of Sudanese pediatric patients in this study using PCR and IHC which is much over than the report in 2012 from the same country by Bilal and Elshibly (2012) who reported a rate of (10%), and even much over than report of similar study from Greece by Papadopouli et al (2009) who reported (12%) in 2009. This may be attributed to the low specificity and sensitivity of other technique and strategies for the diagnosis of the lymphadenopathy, that may have a false negative rate of would have been more yielding if combined with PCR, a costly tool of diagnosis in a developing country .…”

Section: Discussioncontrasting

confidence: 50%

Frequency of Tuberculous Lymphadenitis among Sudanese Pediatric patients

Ahmed

Nourein

Salih

2014

Egyptian Academic Journal of Biological Sciences. C, Physiology

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Background: Tuberculosis (TB) is one of the major health challenges in many developing countries and in Sudan in particular. The aim of this study was to screen pediatric patients suspected with lymph Node (LN) TB for the presence of tuberculosis. Methodology: This study investigated retrospectively 42 LN biopsies taken from pediatric patients for evidences indicating the presence of Mycobacterium Tuberculosis (MT). Hematoxylin and Eosin (HE), Zielnelson (ZN), Immunohistochemistry (IHC) and Polymerase Chain Reaction (PCR) techniques were used for diagnosis. Results: For HE giant cell granuloma and caseation were evidenced in 33/42(78.6%), since epitheloid granuloma was evidenced in 9/42(21.4%). Positive ZN, IHC and PCR were indicated in 1/42(2.4%), 33/42 (78.6%) and 33/42(78.6%), respectively. Conclusion: pediatric TB is still prevalent in some parts of Sudan. More effective health strategies are urgently needed in Sudan, particularly in eastern Sudan to control the disease.

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“…This difference is likely because our study focused on patients with asymptomatic lymphadenopathy, thus patients with additional peripheral lymphadenopathy or B symptoms at presentation were excluded [6]. A retrospective cohort study of 50 hospitalized pediatric patients with cervical lymphadenopathy found that abnormal ultrasound characteristics, specifically using the long to short axis and the intranodal vascularity, may help guide the decision for surgical excision [13]. Although our study did not standardize the collection of ultrasound measurements and architecture, we did note that ultrasound findings were often concordant with final pathology; together these data support that ultrasonography remains a useful, low-risk option to help risk-stratify patients with cervical lymphadenopathy.…”

Section: Discussionmentioning

confidence: 99%

Management of Persistent Pediatric Cervical Lymphadenopathy

Wai¹,

Wang²,

Lee³

et al. 2020

AOHNS

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Clinical data extracted from charts included pertinent antecedent symptoms, medical history, and physical exam features including lymph node location, consistency, and overlying skin changes. Lymph node location were classified as follows: anterior cervical (defined as lymphadenopathy overlying the sternocleidomastoid or anterior to the muscle), posterior cervical (any lymph node posterior to the sternocleidomastoid), submandibular, submental, postauricular and supraclavicular. All lymphadenopathy dimensions, noted on either physical exam or ultrasound report, were reported using the largest dimension. If multiple lymph nodes were present, the largest lymph node was used. Ultrasound imaging reports were also reviewed for any commentary on nodal architecture or abnormal features.

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Cervical Lymphadenopathy in Childhood Epidemiology and Management

Cited by 8 publications

References 9 publications

Pattern of Head and Neck Malignancies in North Eastern India - A Hospital Based Prospective Study

Pattern of Head and Neck Malignancies in North Eastern India - A Hospital Based Prospective Study

Frequency of Tuberculous Lymphadenitis among Sudanese Pediatric patients

Management of Persistent Pediatric Cervical Lymphadenopathy

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