Cervical lymph node tuberculosis in Libreville: Epidemiology, diagnosis, and therapy

Mouba, John Florent; Miloundja, Jérôme; Mimbila-Mayi, Mylène; Ndjenkam, Florent Tchouansi; N'Zouba, L.

doi:10.1684/san.2011.0269

Cited by 6 publications

(5 citation statements)

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“…Our loss to follow up rate of 28% for the years 2008–2011 is in accordance, albeit on the lower end, with others who found rates between 26 and 61% . The absence of systematic records on long‐term outcome of TB patients also indicates sub‐optimal follow up.…”

Section: Discussionsupporting

confidence: 89%

Tuberculosis patients hospitalized in the Albert Schweitzer Hospital, Lambaréné, Gabon—a retrospective observational study

Stolp

Huson

Janssen

et al. 2013

Clinical Microbiology and Infection

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Epidemiological data on tuberculosis in Central Africa are limited. We performed a retrospective observational study on clinical characteristics of 719 hospitalized tuberculosis patients in Lambaréné, Gabon. Human immunodeficiency virus (HIV) co-infection rate was high (34%) and in-hospital mortality was significantly higher in HIV-positive patients (10% versus 2%). Long-term information on patient outcome was limited; however, from 2008 to 2011, loss to follow up was noted in 28% of cases. Our data illustrate the high burden of TB in Gabon, where loss to follow up and emerging drug resistance are important problems for which comprehensive data are still lacking.

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Section: Discussionsupporting

confidence: 89%

Tuberculosis patients hospitalized in the Albert Schweitzer Hospital, Lambaréné, Gabon—a retrospective observational study

Stolp

Huson

Janssen

et al. 2013

Clinical Microbiology and Infection

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“…In our study, the main reason for consultation was cervical swelling in 100 patients (i.e., 96.2%). This is similar to the data in the literature with rates ranging from 74% [23] up to 100% [24]. According to our results, consultation time varied between 3 weeks and 7 months, which is consistent with most studies [24,25].…”

Section: Discussionsupporting

confidence: 93%

“…This is similar to the data in the literature with rates ranging from 74% [23] up to 100% [24]. According to our results, consultation time varied between 3 weeks and 7 months, which is consistent with most studies [24,25]. On the other hand, another study reported a longer delay of up to 9 months instead of 7 [26].…”

Section: Discussionsupporting

confidence: 92%

The Role of Surgery in the Treatment of Cervical Lymph Node Tuberculosis

Tahiri,

Yacoubi,

Elhouari

et al. 2023

Cureus

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Cervical lymph node tuberculosis is a public health problem in Morocco and the rest of the world. Its paucibacillary nature makes diagnosis and treatment difficult. This is a descriptive-analytical retrospective study presenting 104 cases of patients with manifestations of cervical lymph node tuberculosis confirmed by pathological examination (100%), associated in some cases with positive bacteriology (40.6%), treated and followed up in the otolaryngology (ENT) department of the Cheikh Khalifa International University Hospital (HUICK) over a period of 5 years and 9 months (from January 01, 2017, to September 30, 2022).In our study, 14 patients (i.e., 13.5%) had a history of tuberculosis (all locations); only four (i.e., 3.8%) of them had confirmed cervical lymph node tuberculosis, of which three were still under treatment: two of them presented for treatment failure (i.e., 1.9%) and one patient for a paradoxical reaction (i.e., 1%). Three pulmonary locations (i.e., 2.9%) and one mediastinal location (i.e., 1%) were found. Surgery associated with histological study was the key to the diagnosis of tuberculosis in our study. Its procedures were: excisional biopsy for 26 patients (i.e., 25%), adenectomy for 54 patients (i.e., 51.9%), lymph node dissection for 15 patients (i.e., 14.4%), and lymphadenectomy for nine patients (i.e., 8.7%). In some cases, drainage (+/curettage) was recommended in addition to the surgical procedure in 14 patients (i.e., 13.5%). All our patients benefited from post-surgical anti-bacillary treatment. Lymphorrhea was the only operative complication and it affected two patients (i.e., 1.9%). Meanwhile, the relapse rate was 10.6% (i.e., 11 patients), the treatment failure rate was 3.8% (i.e., four patients), and the paradoxical reaction affected 2.9% (i.e., three patients). The latter had all benefited from a simple biopsy. This indicates that a more extensive surgical procedure gives better results with a better healing rate.In conclusion, anti-bacillary treatment remains the reference treatment for lymph node tuberculosis. However, surgery holds great promise as the first-line treatment in case of fistula or abscess or in the event of failure or if complications occur.

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“…According to a French study, this proportion was 25% among lymph node TB patients [44]. Another study from Gabon reported that the proportion among cervical lymph node TB patients was 24.3% [45]. In India, among the miliary tuberculosis patients presenting with neurological manifestations, the proportion was 10% [46].…”

Section: Proportion Of Ltfumentioning

confidence: 99%

Loss to Follow-Up (LTFU) during Tuberculosis Treatment

Lin¹

2019

Healthcare Access - Regional Overviews [Working Title]

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Loss to follow-up (LTFU) is a serious issue in the field of tuberculosis (TB) since it can lead to TB outbreaks and drug resistance. The proportion of LTFU patients differs among different countries, regions, year, and institutions. In some countries, the number of patients that were LTFU nearly reaches half of the total patients. Underlying factors such as age, gender, education, residence, financial factors, migration, and social stigma are discussed in this chapter. These factors should always be taken into consideration whenever a treatment program is designed. Suggestions have been made regarding some interventions that could potentially solve the problem of LTFU. With these points in mind, an ambitious approach should be taken to reduce the number of LTFU patients up to zero.

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Cervical lymph node tuberculosis in Libreville: Epidemiology, diagnosis, and therapy

Cited by 6 publications

References 0 publications

Tuberculosis patients hospitalized in the Albert Schweitzer Hospital, Lambaréné, Gabon—a retrospective observational study

Tuberculosis patients hospitalized in the Albert Schweitzer Hospital, Lambaréné, Gabon—a retrospective observational study

The Role of Surgery in the Treatment of Cervical Lymph Node Tuberculosis

Loss to Follow-Up (LTFU) during Tuberculosis Treatment

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