Cervical intramedullary cavernous angioma with MRI-proven haemorrhages

Mehdorn, H. M.; Stolke, D.

doi:10.1007/bf00314647

Cited by 27 publications

(11 citation statements)

References 36 publications

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“…Human spinal cord cavernous hemangiomas are T1‐ and T2‐hyperintense with minimal or no contrast enhancement . A target‐like appearance of cavernous hemangiomas has also been reported in people with the center being T2‐hyperintense surrounded by a T2‐hypointense rim due to hemosiderin .…”

Section: Discussionmentioning

confidence: 98%

Imaging Diagnosis—spinal Cord Hemangioma in Two Dogs

Jull

Walmsley

Benigni

et al. 2011

Vet Radiology Ultrasound

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Intramedullary masses are a dilemma due to the limited access for a nonsurgical biopsy, thus, accurate imaging characterization is crucial. Magnetic resonance imaging findings of two confirmed canine thoracic intramedullary hemangiomas are described. A capillary hemangioma was of mixed intensity but predominantly T2-hyperintense and mildly T1-hyperintense to spinal cord with strong contrast enhancement. A cavernous hemangioma had a target-like appearance in both T1-weighted (T1w) and T2-weighted (T2w) images. In T2w images there was a small isointense center surrounded by a relatively large hyperintense area. In T1w images, there was a large isointense centre with a relatively small hyperintense periphery. Such characteristics should prioritize hemangioma as a consideration in a progressive myelopathy due to an intramedullary mass.

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Section: Discussionmentioning

confidence: 98%

Imaging Diagnosis—spinal Cord Hemangioma in Two Dogs

Jull

Walmsley

Benigni

et al. 2011

Vet Radiology Ultrasound

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“…32 There have been previous cases of intramedullary CMs reported in the literature (Table 3), and there has been an increased number of case reports and small series in the MR imaging era. [2][3][4][5][6][8][9][10][12][13][14][15]17,19,20,[22][23][24][25][26][27][28][30][31][32][33][34][35][36][37][38][39][40][41] A female/male ratio of 2:1 had been previously reported. 1 However, we previously calculated an equal distribution for all spinal intramedullary CMs reported in the literature.…”

Section: Discussionmentioning

confidence: 98%

Clinical presentation and optimal management for intramedullary cavernous malformations

Jallo¹,

Freed²,

Zareck³

et al. 2006

FOC

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Object Intramedullary cavernous malformations (CMs) account for approximately 5% of all intraspinal lesions. The purpose of this study was to define the spectrum of presentation for spinal intramedullary CMs and the results of microsurgery for these benign but clinically progressive lesions. Methods Retrospective chart review was performed in 26 patients with histologically diagnosed CMs. All patients had undergone preoperative magnetic resonance (MR) imaging studies. All patients were treated with a laminectomy and microsurgical resection of the malformation. Conclusions The MR imaging findings are diagnostic for intramedullary CMs; these lesions abut a pial surface and have a characteristic imaging pattern. Spinal intramedullary CMs present with either an acute onset of neurological compromise or a slowly progressive neurological decline. Acute neurological decline occurs secondary to hemorrhage inside the spinal cord. Chronic progressive myelopathy occurs due to microhemorrhages and resulting gliotic reaction to blood products. Surgery and total removal of the lesion tends to halt progression of symptoms.

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“…The acute type, with a sudden onset of neurological No. patient number, Age in years, F female, M male, Duration duration of symptoms to admission, C cervical, T thoracal, L lumbar deterioration, is usually caused by space occupying haemorrhage in about 70% and acute decompensation due to mass effect, with previous minor complaints [15,17,21]. In comparison to this, various neurofunctional impairments develop slowly and progressively due to recurrent microhaemorrhages, mass effect, embolism and gliosis [3,7].…”

Section: Discussionmentioning

confidence: 99%

“…Cavernous malformations (CMs) are angiographically occult, mulberry like dynamic vascular lesions, which account up to 15% of all the vascular malformations and occur throughout the central nervous system (CNS) [2,11,14,21,23]. An association with a venous anomaly is always given [4,25].…”

Section: Introductionmentioning

confidence: 99%

“…Due to space occupying growth, recurrent micro-bleeding or significant haemorrhage (in respect of the available space) spinal CMs can lead to severe neurological deteriorations, such as progressive myelopathy and right up to paraplegia, unlike their intracranial counterparts. The latter typically presents with seizures, progressive focal neurological deficits and haemorrhage, whereas the risk of significant haemorrhage like other vascular malformations is considered to be low due to the low venous pressure [2,21].…”

Section: Introductionmentioning

confidence: 99%

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Symptomatic spinal cavernous malformations: indication for microsurgical treatment and outcome

et al. 2011

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Purpose We demonstrate clinical features, therapy and outcome of 14 patients with symptomatic spinal cavernous malformations (CM). Methods We retrospectively reviewed all patients who underwent microsurgical treatment of symptomatic spinal CM during the last decade in our department through an analysis of our database. Results We analyzed the data of 14 patients (11 females, 3 males) with symptomatic spinal CM in a range of 16-77 years (mean age 47.8 years). Seven patients (50%) experienced significant improvement of their symptoms rapidly after surgery. The remaining seven patients presented new non pre-existing complaints, which improved gradually with a favourable outcome at the last follow-up examination in six cases. Conclusion Microsurgical treatment under perioperative electrophysiological monitoring is justified to prevent severe neurofunctional deterioration in symptomatic spinal CM. Although some of the patients deteriorate after surgery, the symptoms are rapidly declining with a favourable outcome in majority of them.

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Cervical intramedullary cavernous angioma with MRI-proven haemorrhages

Cited by 27 publications

References 36 publications

Imaging Diagnosis—spinal Cord Hemangioma in Two Dogs

Imaging Diagnosis—spinal Cord Hemangioma in Two Dogs

Clinical presentation and optimal management for intramedullary cavernous malformations

Symptomatic spinal cavernous malformations: indication for microsurgical treatment and outcome

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