Cervical cancer mortality among young women in Latin America and the Caribbean: trend analysis from 1997 to 2030

Abstract

Background Cervical cancer continues to show a high burden among young women worldwide, particularly in low- and middle-income countries. Limited data is available describing cervical cancer mortality among young women in Latin America and the Caribbean (LAC). The purpose of this study was to examine the mortality trends of cervical cancer among young women in LAC and predict mortality rates to 2030. Methods Deaths from cervical cancer were obtained from the World Health Organization mortality database. Age-standardized mortality rates per 100,000 women-years were estimated in women aged 20–44 years using the world standard population for 16 countries (and territories) in LAC from 1997 to 2017. We estimated the average mortality rates for the last 4 years (2014–2017). Joinpoint regression models were used to identify significant changes in mortality trends. Nordpred method was used for the prediction of the mortality rates to 2030. Results Between 2014 and 2017, Paraguay and Venezuela had the highest mortality rates of cervical cancer, whereas Puerto Rico had the lowest rates. Overall, most of the LAC countries showed downward trends of cervical cancer mortality over the entire period. Significant decreases were observed in Chile (Average annual percent change [AAPC]: − 2.4%), Colombia (AAPC: − 2.0%), Cuba (AAPC: − 3.6%), El Salvador (AAPC: − 3.1%), Mexico (AAPC: − 3.9%), Nicaragua (AAPC: − 1.7%), Panama (AAPC: − 1.7%), and Peru (AAPC: − 2.2%). In contrast, Brazil (AAPC: + 0.8%) and Paraguay (AAPC: + 3.7%) showed significant upward trends. By 2030, mortality rates are not predicted to further decrease in some LAC countries, including Argentina, Paraguay, and Venezuela. Conclusions Mortality trends of cervical cancer among young women have large variability in LAC countries. Cervical cancer screening programs have a high priority for the region. Primary and secondary prevention in the community are necessary to accelerate a reduction of cervical cancer mortality by 2030.

Patient delay and related influencing factors in Chinese women under 35 years diagnosed with cervical cancer: A cross-sectional study

“…The present results showed that the status quo of timely health seeking is not optimistic in this population; diagnosis delay and disease progression caused by patient delay might be important reasons for the poor prognosis in this population. 3 , 8 The overall trend demonstrated a decline in cervical cancer mortality, while cervical cancer deaths tended to occur in younger age-groups 2 , 36 (up to 5.5% annually). 5 …”

“… 1 China contributes to more than 18% of the global cervical cancer burden, with 106,000 cases and 48,000 deaths. 1 Human suffering, societal burden, and high economic costs associated with cancer have been reported in many countries 2 , 3 , 4 , including China. 2 Although the maximum incidence rate is recorded around the age of 40 years, the number of cervical cancer cases is increasing at an alarming rate among younger women in China, 5 that is, approximately 11 cases per 100,000, with an annual increase of 3.05% ( P ​< ​0.001).…”

“… 2 Although the maximum incidence rate is recorded around the age of 40 years, the number of cervical cancer cases is increasing at an alarming rate among younger women in China, 5 that is, approximately 11 cases per 100,000, with an annual increase of 3.05% ( P ​< ​0.001). 6 High frequencies of cervical adenocarcinoma 7 and lymphatic metastasis 3 have been identified in young women, especially in those who are < 35 years old; those with aggressive tumors have a poor prognosis. 8 , 9 These factors make early diagnosis of cervical cancer in women an important societal target worldwide.…”

The health system and access to treatment in patients with cervical cancer in Mexico

“…Among women with invasive CC, around 70% are diagnosed with locally advanced disease. These figures speak on deficiencies in coverage and timely diagnosis and treatment of detected preinvasive and invasive lesions (2)(3)(4).…”

Laparoscopic Versus Abdominal Radical Hysterectomy for Cervical Cancer

“…1,2 There are about 500,000 new cases of cervical cancer every year in the world, 85% of which are in developing countries, and about 250,000 people die of cervical cancer each year. 3,4 In China, 140,000 new cases are discovered every year, accounting for about one third of the global patients with cervical cancer, and about 50,000 patients die of cervical cancer every year. 5,6 In recent years, the incidence of cervical cancer has a younger trend.…”