Certain perspectives about the use of corticosteroids for managing hospitalized patients with rheumatic diseases

Challenging issues in rheumatology: thoughts and perspectives

“…Rheumatology's modern history can be characterized by defining themes, and challenges, in each decade, to which we have adapted well (Table 1). The introduction of glucocorticoids by Philip Hench and colleagues at the Mayo Clinic in the 1950s transformed clinical medicine [2]. The 1960s saw the establishment, development, and growth of rheumatology training programs.…”

Synthetic Corticosteroids As Tryptophan Hydroxylase Stabilizers

“…Corticosteroid drugs have been widely used in clinical practice since the 1950s. They are highly effective in treating a wide variety of acute inflammatory diseases [1], including asthma, chronic obstructive pulmonary disorder [2], systemic lupus erythematosus [3], cancer [4], rheumatoid arthritis [5], and autoimmune pancreatitis [6]. Their antiinflammatory action also has beneficial effects in patients with acute respiratory distress syndrome (e.g., as a consequence of COVID-19) [7].…”