Cerium Oxide-Decorated γ-Fe2O3 Nanoparticles: Design, Synthesis and in vivo Effects on Parameters of Oxidative Stress

Moskvin, M. D.; Marková, Irena; Malínská, Hana; Miklánková, Denisa; Hüttl, Martina; Oliyarnyk, Olena; Pop‐Georgievski, Ognen; Zhigunov, Alexander; Petrovský, Eduard

doi:10.3389/fchem.2020.00682

Cited by 20 publications

(15 citation statements)

References 37 publications

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“…The bending vibration of the Ce–O–Si bond shows an extra signal at 685.66 cm –1 and a signal at 434.20 cm –1 due to the bending vibration of the Fe–O bonding. 78 …”

Section: Resultsmentioning

confidence: 99%

Magnetically Recoverable Silica-Decorated Ferromagnetic-Nanoceria Nanocatalysts and Their Use withO- andN-Butyloxycarbonylation Reaction via Solvent-Free Condition

Patil

Tandon

2022

ACS Omega

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Silica-decorated ferrite nanoparticles, a new kind, coated with ceric ammonium nitrate (CAN), have been prepared successfully by simple coprecipitation techniques. Powder X-ray diffraction spectroscopy (PXRD), Fourier transform-infrared spectroscopy (FT-IR), field emission-scanning electron microscope (FE-SEM), wavelength-dispersive X-ray spectroscopy (WDX), energy-dispersive spectroscopy (EDS), inductive coupled plasma-optical emission spectroscopy (ICP-OES), and thermogravimetric analysis (TGA) techniques were used to characterize these nanoparticles. The catalysts are further studied for catalytic activity in solvent-free conditions. Importantly, these nanoparticles have been collected from the reaction mixture using an external magnet and recycled up to minimum of 15 cycles with no substantial loss of catalytic characteristics.

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“…The bending vibration of the Ce–O–Si bond shows an extra signal at 685.66 cm –1 and a signal at 434.20 cm –1 due to the bending vibration of the Fe–O bonding. 78 …”

Section: Resultsmentioning

confidence: 99%

Magnetically Recoverable Silica-Decorated Ferromagnetic-Nanoceria Nanocatalysts and Their Use withO- andN-Butyloxycarbonylation Reaction via Solvent-Free Condition

Patil

Tandon

2022

ACS Omega

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“…After incubation for 24 h, the SOD and CAT concentrations were determined according to the manufacturer’s instructions. 28 …”

Section: Methodsmentioning

confidence: 99%

Preparation, Biocompatibility and Antitumor Activity of Nanodelivery System Targeting Breast Cancer Base on a Silica Nanoparticle

Liu¹,

Ren²,

Zhang³

et al. 2021

OTT

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Background: Breast cancer (BC) is the most common type of cancer among women worldwide, and about 30% of males will have recurrent disease. Methods: In order to treat recurrent BC, we designed a type of silica nanodelivery system loaded with epirubicin and curcumin (composite nanoparticles, CNPs). To promote CNPs clinical application, the stability, the blood, immune and cell compatibility, skin stimulation experiments, anti-tumor activity in vivo and in vitro were studied. Results: In our study, the CNPs had a particle size of 73.9 nm and a uniform size and morphology; moreover, they maintained physical and chemical stability in the blood protein environment. Additionally, results showed that nanoparticles had good blood and immune compatibility, and they did not affect intracellular superoxide dismutase (SOD) and intracellular catalase (CAT). Skin stimulation experiments showed that CNPs did not cause any obvious irritative damage to the intact skin of rabbits. In the cytotoxicity study, CNPs showed strongest antitumor activity. The results of cell cycle and apoptosis studies showed that CNPs could mainly induce apoptosis of S and G2/M phase cells. In vivo, CNPs showed strongest aggregation in the tumor after 6 h of tail vein administration, and a large amount of CNPs continued to accumulate in the blood after 12 h of administration, indicating that CNPs had long circulation ability. The in vivo antitumor activities showed that CNPs had the strongest antitumor activity and tumor targeting ability, and hematoxylin-eosin staining of internal organs showed no obvious difference between treatment groups and negative control. Conclusion:CNPs have an ideal biosafety and therapeutic effect for recurrent BC, and they have potential clinical application value.

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“…In a preclinical AD mouse model, ceria NPs coupling with triphenylphosphonium (TPP) localize in the mitochondria and prevent neuronal death (Kwon et al, 2016). In another study, γ-FeO3/CeOx@PEG2,000 NPs could effectively scavenge radicals and decrease the oxidative stress (Horák et al, 2020).…”

Section: Cerium Npsmentioning

confidence: 95%

Nanomedicine: A Promising Way to Manage Alzheimer’s Disease

Khan

Mir

Ngowi

et al. 2021

Front. Bioeng. Biotechnol.

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Alzheimer’s disease (AD) is a devastating disease of the aging population characterized by the progressive and slow brain decay due to the formation of extracellular plaques in the hippocampus. AD cells encompass tangles of twisted strands of aggregated microtubule binding proteins surrounded by plaques. Delivering corresponding drugs in the brain to deal with these clinical pathologies, we face a naturally built strong, protective barrier between circulating blood and brain cells called the blood–brain barrier (BBB). Nanomedicines provide state-of-the-art alternative approaches to overcome the challenges in drug transport across the BBB. The current review presents the advances in the roles of nanomedicines in both the diagnosis and treatment of AD. We intend to provide an overview of how nanotechnology has revolutionized the approaches used to manage AD and highlight the current key bottlenecks and future perspective in this field. Furthermore, the emerging nanomedicines for managing brain diseases like AD could promote the booming growth of research and their clinical availability.

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Cerium Oxide-Decorated γ-Fe2O3 Nanoparticles: Design, Synthesis and in vivo Effects on Parameters of Oxidative Stress

Cited by 20 publications

References 37 publications

Magnetically Recoverable Silica-Decorated Ferromagnetic-Nanoceria Nanocatalysts and Their Use withO- andN-Butyloxycarbonylation Reaction via Solvent-Free Condition

Magnetically Recoverable Silica-Decorated Ferromagnetic-Nanoceria Nanocatalysts and Their Use withO- andN-Butyloxycarbonylation Reaction via Solvent-Free Condition

Preparation, Biocompatibility and Antitumor Activity of Nanodelivery System Targeting Breast Cancer Base on a Silica Nanoparticle

Nanomedicine: A Promising Way to Manage Alzheimer’s Disease

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