Cerebrovascular Diseases

Teramoto, Tamio; Sasaki, Jun; Ishibashi, Shun; Birou, Sadatoshi; Daida, Hiroyuki; Dohi, Seitaro; Egusa, Genshi; Hiro, Takafumi; Hirobe, Kazuhiko; Iida, Mami; Kihara, Shinji; Kinoshita, Makoto; Maruyama, Chizuko; Ohta, Takao; Okamura, Tomonori; Yamashita, Shizuya; Yokode, Masayuki; Yokote, Koutaro

doi:10.5551/jat.19661

Cited by 1 publication

(1 citation statement)

References 38 publications

(29 reference statements)

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“…Surprisingly, several studies in the general Japanese population showed that total mortality was decreased in subjects with higher total cholesterol levels or hyperlipidemia 48,49) , while a nationwide study showed that subjects with the highest total cholesterol levels had the highest total mortality [50][51][52] . Thus, to examine this issue further, we determined the association between total cholesterol levels [divided into three groups, high (total cholesterol ≥ 240 mg/dL), middle (180 -239 mg/dL), and low (≤ 179 mg/dL)] and total mortality in our study sample.…”

Section: Acknowledgementsmentioning

confidence: 99%

Association of Treatment for Hyperlipidemia with Decreased Total Mortality in Japanese Individuals: the Yamagata (Takahata) Study

Daimon

Oizumi

Kameda

et al. 2015

J Atheroscler Thromb

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Aim:To evaluate the effects of treatment for hyperlipidemia on total mortality, we examined the association with adjustments for multiple factors, including those related to general health, such as blood hemoglobin and serum levels of albumin, adiponectin, brain natriuretic peptide, and lipids, using a prospective cohort study of a general Japanese population. Conclusions: Not only antihyperlipidemic drugs used but also selection bias and non-evaluated factors, such as socio-economic status, educational level, health literacy, and daily nutrition, affected the results. Subjects taking treatment for hyperlipidemia were found to have reduced total mortality, which was independent of serum lipid levels.

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