Cerebrovascular complications of fibromuscular dysplasia

Leary, Megan; Finley, Anna J; Caplan, Louis R.

doi:10.1007/s11936-996-0019-5

Cited by 9 publications

(9 citation statements)

References 95 publications

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“…Patients frequently complain of tinnitus, described as swishing synchronous with the pulse and loudest over the involved carotid artery [66]. In some instances, cerebrovascular FMD is diagnosed as the cause of an asymptomatic cervical bruit or when angiography, MRA, or CTA are performed for unrelated reasons [11,67]. • Fibromuscular dysplasia of the carotid or vertebral arteries may result in transient ischemic attack, amaurosis fugax, stroke, Horner's syndrome, or cranial nerve palsies [13,65].…”

Section: Cerebrovascular Fmdmentioning

confidence: 99%

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Fibromuscular dysplasia

Slovut¹,

Olin

2005

Curr Treat Options Cardio Med

193

100

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The most common clinical manifestations of fibromuscular dysplasia (FMD) are hypertension due to renal artery involvement and transient ischemic attack or stroke due to carotid or vertebral artery involvement. Patients with renal artery FMD and hypertension should undergo primary angioplasty with the goal of curing the hypertension. If the blood pressure fails to normalize following angioplasty, the physician should institute antihypertensive medications according to the recommendations of the Joint National Committee on the Prevention, Detection, and Treatment of High Blood Pressure VII. In patients with cerebrovascular FMD, antiplatelet agents represent the cornerstone of therapy. Percutaneous angioplasty has emerged as the preferred treatment for symptomatic cerebrovascular FMD.

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Section: Cerebrovascular Fmdmentioning

confidence: 99%

“…In one study of 49 patients who had involvement of 88 internal carotid arteries, all patients who were initially asymptomatic remained so during follow-up [74]. Antiplatelet agents, such as aspirin or clopidogrel, may be reasonable agents for stroke prevention in patients with cerebrovascular FMD [67]. …”

Section: Medical Managementmentioning

confidence: 99%

Fibromuscular dysplasia

Slovut¹,

Olin

2005

Curr Treat Options Cardio Med

193

100

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“…Intracranial arteries are involved in 7% to 20% of cases of cervicoencephalic FMD [8]. Most cervico-encephalic FMD are located in the ICA, most commonly in the middle or distal segments.…”

Section: Discussionmentioning

confidence: 99%

Fibromuscular dysplasia of internal carotid arteries: features on high-resolution magnetic resonance imaging

et al. 2022

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Fibromuscular dysplasia (FMD) is a noninflammatory and nonatherosclerotic disease that predominantly affects the renal and internal carotid arteries. However, the cause of this disease remains unclear. Radiological studies are important diagnostic methods, which generally involve luminal features on computed tomographic angiography, magnetic resonance angiography, and digital subtraction angiography. However, the high-resolution magnetic resonance imaging (HR-MRI) features of FMD have not yet been reported. Herein, we report the HR-MRI features of patients with FMD who showed typical involvement of the internal carotid arteries. Although both patients presented a beading appearance typical of medial fibroplasia, HR-MRI nevertheless showed distinct features. HR-MRI revealed concentric wall thickening and circular enhancement with dystrophic calcification in one and wall thickening, but no enhancement in the others. Further studies are required to determine whether these HR-MRI features are related to the type of FMD or patient prognosis.

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“…[187][188][189] The renal arteries are the most commonly involved, causing renovascular hypertension. [187][188][189] The renal arteries are the most commonly involved, causing renovascular hypertension.…”

Section: Fibromuscular Dysplasiamentioning

confidence: 99%