Cerebrovascular accident with quadriplegia following postpartum eclampsia

Okafor, Ugochukwu Vincent; Efetie, ER; Onwuekwe, Ikenna; Uwaezeoke, T. C.

doi:10.1111/j.1399-6576.2006.00920.x

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…Studies reporting impact of HCW strikes on the implementation of prospective trials are lacking. A few studies have reported deleterious effects of Nigerian HCW strikes on patient care, including maternal morbidity and mortality [ 42 , 43 ], and missed appointments for acute and chronic eye care [ 44 ]. Given the significant impact of HCW strikes on participants and projects, all four IR teams developed implementation plans with extra time built-in to allow for these occurrences.…”

Section: Discussionmentioning

confidence: 99%

Generating evidence for health policy in challenging settings: lessons learned from four prevention of mother-to-child transmission of HIV implementation research studies in Nigeria

Sam-Agudu

Aliyu

Adeyemi

et al. 2018

Health Res Policy Sys

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BackgroundImplementation research (IR) facilitates health systems strengthening and optimal patient outcomes by generating evidence for scale-up of efficacious strategies in context. Thus, difficulties in generating IR evidence, particularly in limited-resource settings with wide disease prevention and treatment gaps, need to be anticipated and addressed. Nigeria is a priority country for the prevention of mother-to-child transmission of HIV (PMTCT). This paper analyses the experiences of four PMTCT IR studies in Nigeria, and proffers solutions to major challenges encountered during implementation.Studies included and findingsMulticentre PMTCT IR studies conducted in Nigeria during the Global Plan’s assessment period (2011 to 2015) were included. Four studies were identified, namely The Baby Shower Trial, Optimizing PMTCT, MoMent and Lafiyan Jikin Mata. Major common challenges encountered were categorised as ‘External’ (beyond the control of study teams) and ‘Internal’ (amenable to rectification by study teams).External challenges included healthcare worker strikes and turnover, acts and threats of ethnic and political violence and terrorism, and multiplicity of required local ethical reviews. Internal challenges included limited research capacity among study staff, research staff turnover and travel restrictions hindering study site visits. Deliberate research capacity-building was provided to study staff through multiple opportunities before and during study implementation. Post-study employment opportunities and pathways for further research career-building are suggested as incentives for study staff retention. Engagement of study community-resident personnel minimised research staff turnover in violence-prone areas.ConclusionsThe IR environment in Nigeria is extremely diverse and challenging, yet, with local experience and anticipatory planning, innovative solutions can be implemented to modulate internal challenges. Issues still remain with healthcare worker strikes and often unpredictable insecurity. There is a dire need for cooperation between institutional review boards across Nigeria in order to minimise the multiplicity of reviews for multicentre studies. External challenges need to be addressed by high-level stakeholders, given Nigeria’s crucial regional and global position in the fight against the HIV epidemic.

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Section: Discussionmentioning

confidence: 99%

Generating evidence for health policy in challenging settings: lessons learned from four prevention of mother-to-child transmission of HIV implementation research studies in Nigeria

Sam-Agudu

Aliyu

Adeyemi

et al. 2018

Health Res Policy Sys

View full text Add to dashboard Cite

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Eclampsia in Janakpur Zonal Hospital, Nepal: Favourable outcome with Magnesium sulphate

Jha¹,

Verma²,

Jha³

1970

Nepal j. obstet. gynaecol.

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Aim: To determine the demographic characters of patients of eclampsia and the effectiveness of Magnesium Sulphate in terms of maternal and perinatal outcome. Methods: A prospective study of the eclamptic patients was conducted from 18 th Aug -17 th Oct 2006 (1 Bhadra 2063 to 30 Ashwin 2063) attending the Obstetric Department of Janakpur Zonal Hospital (JZH). Results: Of the 50 eclamptic women [antepartum 80%, intrapartum 6 % and postpartum 14%] with overall improvement in 92% although 2 cases had to be referred to center with ICU facility and 2 cases died. The demographic characteristics were young primiparous population of low socioeconomic condtion. Caesarean was done for 48 %. Pretermaurity was seen in 50% and 76% were live birth. Conclusions: Nepal has a high maternal mortality rate and eclampsia is a big contributing factor, which could be reduced by using magnesium sulphate widely in all parts of Nepal taking, ours as one of the peripheral hospital as an example.

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Cerebrovascular accident with quadriplegia following postpartum eclampsia

Cited by 2 publications

References 8 publications

Generating evidence for health policy in challenging settings: lessons learned from four prevention of mother-to-child transmission of HIV implementation research studies in Nigeria

Generating evidence for health policy in challenging settings: lessons learned from four prevention of mother-to-child transmission of HIV implementation research studies in Nigeria

Eclampsia in Janakpur Zonal Hospital, Nepal: Favourable outcome with Magnesium sulphate

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