Cerebrospinal Fluid Spread of Anaplastic Glioma

Cytomorphologic and clinicoradiologic analysis of primary nonhematologic central nervous system tumors with positive cerebrospinal fluid

“…Leptomeningeal seeding of high‐grade infiltrating gliomas, although uncommon in the past, has become increasingly evident in recent years with overall improved survival . High‐grade infiltrating gliomas, including anaplastic astrocytomas (World Health Organization [WHO] grade III), anaplastic oligodendroglioma (WHO grade III), and glioblastomas (WHO grade IV), were the second most common primary CNS tumors with positive CSF cytology noted in the current study.…”