Cerebrospinal fluid neopterin and CXCL13 are suitable biomarkers for staging and detection of treatment failure in a non-human primate model of human African trypanosomiasis
Abstract:Background
Follow-up of treated human African trypanosomiasis (HAT) patients has been a routine practice for confirming cure and early detection of treatment failure.
Objective
The aim of this study was to verify suitability of neopterin and CXCL13 as disease stage biomarkers and monitors of treatment efficacy in a vervet monkey model of HAT.
Methods
Six monk… Show more
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